NCT06401733Completed
Intensive Aerobic and Resistance Exercise Program (IAREP)
Metabolic, Inflammatory, Cognitive Risk Stratification, and Intensive Aerobic and Resistance Exercise Intervention for Middle-aged and Older Adults With Type 2 Diabetes Mellitus
Source: ClinicalTrials.gov · Last updated 19 Feb 2026
Brief summary (registry, in English)
A 12-week Intensive Aerobic and Resistance Exercise Program (IAREP) intervention was implemented on high-risk and low-risk subjects with cognitive impairment in type 2 Diabetes Mellitus. The study aims to evaluate the effectiveness of IAREP on cognition, metabolic and inflammatory health, physical function, vascular health, and health practice behaviour in the Type 2 Diabetes Mellitus population (T2DM).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 58 (actual)
- First submitted
- 27 Apr 2024
- Start date
- 21 Jul 2023
- Primary completion date
- 31 Mar 2025
- Lead sponsor
- National University of Singapore
- Diseases
- Obesity, Type 1 diabetes, Type 2 diabetes
- NCT number
- NCT06401733
What you commit to
- Study type: Interventional
- Participants enrolled: 58
- From 21 Jul 2023 to the primary completion date, 31 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe cognitive (e.g., dementia) or psychiatric disorders (e.g., schizophrenia or severe depression)
- Terminally ill medical conditions (e.g., end stage cancer), severe cardiovascular, respiratory (e.g., respiratory failure), or orthopedic conditions (e.g., freeze shoulder)
- Absolute contraindications to aerobic exercise and resistance training programs (e.g., recent myocardial infarction or electrocardiography changes, complete heart block, acute congestive heart failure, unstable angina, uncontrolled hypertension)
Other
- Severe hearing or vision impairments
- Pregnant or breastfeeding women
- Uncomfortable with video-recording of intervention sessions
Who the study is looking for
- Aged 40 to 85
- Living in the community
- Diagnosed with type 2 diabetes mellitus (T2DM)
- Literate in English or Mandarin
- Activities of daily living (ADL)-independent
- Obtain at least a score of 5 in short physical performance battery (SPPB) test
Age in the registry: 40 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National University Polyclinic (Jurong Polyclinics) Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
Related publications
- A technology-blended exercise intervention for cognitive risk reduction and brain health in middle-aged and older adults with type 2 diabetes in Singapore: a mixed-methods study.J Gerontol A Biol Sci Med Sci · 2026 · PMID 42550210
This page is information, not medical advice. Discuss any trial with your doctor.