NCT06402487CompletedPhase 2/3
Propionic Acid in Multiple Sclerosis
Propionic Acid in Multiple Sclerosis - a Placebo-controlled Randomized Double-blinded Clinical Trial
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
The purpose of this study is to demonstrate the superiority of propionic acid over placebo as add on treatment in multiple sclerosis (MS).
- Status (registry)
- Completed
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 101 (actual)
- First submitted
- 29 Apr 2024
- Start date
- 1 May 2024
- Primary completion date
- 15 Sept 2024
- Lead sponsor
- Salzburger Landeskliniken
- Diseases
- Multiple sclerosis
- NCT number
- NCT06402487
What you commit to
- Study type: Interventional · Phase 2/3
- Participants enrolled: 101
- From 1 May 2024 to the primary completion date, 15 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Change in disease-modifying therapy (DMT) in the previous 4 weeks
- Presence of other concomitant structural nerve diseases (e.g., polyneuropathy, brain tumor, strokes)
Other illness
- Existing severe systemic diseases
Other
- Existing propionic acid supplementation
- High JCV titer under Natalizumab
Who the study is looking for
- Diagnosis of multiple sclerosis (MS)
- Clinically and radiologically stable MS in the previous 3 months
- Age between 18 and 60 years
- Positive finding for oligoclonal bands (OCBs)
- Written consent
- Blood collection at the beginning and end of the study for routine parameter examination as well as sample preservation (especially for measuring propionic acid levels)
- Negative pregnancy test for female participants of childbearing age
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Salzburger Landeskliniken Coordinator of this site? Confirm its status | Salzburg | Austria | Unknown status |
Related publications
- Association of lifestyle and metabolic factors with clinical performance in multiple sclerosis: A cross-sectional study.Med Clin (Barc) · 2026 · PMID 41780143
This page is information, not medical advice. Discuss any trial with your doctor.