NCT06403280Completed
The Effect of Alcohol on Common Tremor Syndromes
The Effect of Alcohol on Common Tremor Syndromes - A Prospective Double-blind Randomised Cross-over (Alcohol, Placebo) Study
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
The aim of this interventional study is to compare the response to alcohol in patients with essential tremor (ET), essential tremor plus (ETplus), dystonic tremor (DT), tremor associated with dystonia (TaD) and tremor in Parkinson´s disease (PD). The main question to be answered is: • Is there a difference in the objective alcohol responsiveness of patients with ET, DT, TaD and PD? Participants will receive either vodka with rum-flavoured orange juice with a target blood alcohol of 0.4 ‰ or a non-alcoholic rum-flavoured orange juice (vice versa on the second study day). Before and 30, 60 an 120 minutes after the study drink the participants will undergo a clinical examination of the tremor and accelerometry will be performed. Researchers will compare alcohol and placebo in a randomized cross over way to see if the effect of alcohol on tremor exceeds the placebo effect.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 45 (actual)
- First submitted
- 29 Apr 2024
- Start date
- May 2024
- Primary completion date
- Dec 2025
- Lead sponsor
- Medical University of Graz
- Diseases
- Parkinson disease
- NCT number
- NCT06403280
What you commit to
- Study type: Interventional
- Participants enrolled: 45
- From May 2024 to the primary completion date, Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- patients with diseases prohibiting alcohol ingestion
- patients with a history of alcohol abuse
Other
- persons that are not willing to abstain from driving at both study days
- pregnancy
Who the study is looking for
- diagnosis of PD, DT, TaD, ET or ETplus based on clinical diagnostic criteria
- tremor in upper extremities
- accompanying person for both study visits
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of Graz Coordinator of this site? Confirm its status | Graz | Austria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.