NCT06405321Recruiting
Conversion or Neoadjuvant Therapy in Hepatocellular Carcinoma
Conversion or Neoadjuvant Therapy in Hepatocellular Carcinoma: A Multicenter Retrospective Study in Guangxi, China (GUIDANCE)
Source: ClinicalTrials.gov · Last updated 14 Jan 2026
Brief summary (registry, in English)
This multicenter retrospective study which included patients with hepatocellular carcinoma (HCC) who received conversion or neoadjuvant therapy to explore the best treatment options and the best benefit group.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 2000 (estimated)
- First submitted
- 4 May 2024
- Start date
- 1 Jan 2019
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Guangxi Medical University
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT06405321
What you commit to
- Study type: Observational
- Planned participants: 2000
- From 1 Jan 2019 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent with other malignancies within 5 years.
Other
- Incomplete medical data.
- Follow-up time less than 3 months.
Who the study is looking for
- Histologically or clinically confirmed diagnosis of HCC.
- Patients who received conversion or neoadjuvant therapy as initial treatment, including hepatic artery infusion chemotherapy (HAIC), transcatheter arterial chemoembolization (TACE), tyrosine kinase inhibitors (TKIs), immune checkpoint inhibitors (ICIs), or radiotherapy.
- Eastern Cooperative Oncology Group performance status (ECOG-PS) of 0 or 1.
- With Child-Pugh 5\~7 scores.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jian-Hong Zhong Coordinator of this site? Confirm its status | Nanning | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.