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NCT06405750Recruiting

Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate

Source: ClinicalTrials.gov · Last updated 15 Jan 2026

Brief summary (registry, in English)

The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram. In connection with the operation, the small pouch known as the auricle of the heart is closed, which can be completely removed after closing. This procedure is common in patients with atrial fibrillation to protect the brain from stroke. In the project, all patients will have this auricle closed if they agree to participate in the project. After closure, the auricle is usually discarded. We will analyze the blood and the auricle tissue taken (if available) in connection with the operation itself, together with the analysis of the electrocardiogram recorded before the planned heart operation.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
1000 (estimated)
First submitted
5 May 2024
Start date
1 Aug 2024
Primary completion date
31 Dec 2035
Lead sponsor
University Hospital Bispebjerg and Frederiksberg
NCT number
NCT06405750

What you commit to

  • Study type: Interventional
  • Planned participants: 1000
  • From 1 Aug 2024 to the primary completion date, 31 Dec 2035
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • current endocarditis
  • follow-up not possible

Who the study is looking for

  • signed informed consent AND
  • planned any open-heart surgery:
    • CABG
    • valve repair or replacement
    • aorta surgery
    • any combination of the above

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Rigshospitalet
Coordinator of this site? Confirm its status
CopenhagenDenmarkRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.