NCT06405750Recruiting
Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
Source: ClinicalTrials.gov · Last updated 15 Jan 2026
Brief summary (registry, in English)
The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram. In connection with the operation, the small pouch known as the auricle of the heart is closed, which can be completely removed after closing. This procedure is common in patients with atrial fibrillation to protect the brain from stroke. In the project, all patients will have this auricle closed if they agree to participate in the project. After closure, the auricle is usually discarded. We will analyze the blood and the auricle tissue taken (if available) in connection with the operation itself, together with the analysis of the electrocardiogram recorded before the planned heart operation.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1000 (estimated)
- First submitted
- 5 May 2024
- Start date
- 1 Aug 2024
- Primary completion date
- 31 Dec 2035
- Lead sponsor
- University Hospital Bispebjerg and Frederiksberg
- Diseases
- Stroke, Atrial fibrillation
- NCT number
- NCT06405750
What you commit to
- Study type: Interventional
- Planned participants: 1000
- From 1 Aug 2024 to the primary completion date, 31 Dec 2035
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- current endocarditis
- follow-up not possible
Who the study is looking for
- signed informed consent AND
- planned any open-heart surgery:
- CABG
- valve repair or replacement
- aorta surgery
- any combination of the above
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.