NCT06408116RecruitingPhase 2
Predicting Esophageal Cancer Borders Using PET-Imaging
Predicting Esophageal Cancer Borders Using PET-Imaging PEGASUS
Source: ClinicalTrials.gov · Last updated 10 Mar 2026
Brief summary (registry, in English)
The study examines the diagnostic precision of endosonography, mpMRI and PET/CT in defining tumor boundaries and tumor spread before and after neoadjuvant therapy and definitive surgery.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 4 Jan 2024
- Start date
- 1 Mar 2024
- Primary completion date
- 31 Jan 2028
- Lead sponsor
- University Hospital Heidelberg
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT06408116
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 30
- From 1 Mar 2024 to the primary completion date, 31 Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous radiation therapy in the tumor region
- Previous tumor disease with \< 5 years of remission
- Surgical therapy is not functionally or technically possible
- Concurrent participation in another clinical trial that could affect the results of this trial or the other trial
- Signs that the person taking part is unlikely to comply with the therapy (e.g. unwillingness to cooperate)
Other illness
- Illnesses that do not allow the person concerned to assess the nature and scope as well as possible consequences of the clinical study
Other
- Distant metastasis
- Patient is not capable of giving consent
- pregnant or breastfeeding women
Who the study is looking for
- Histologically confirmed adenocarcinoma or squamous cell carcinoma of the esophagus, including AEG I and AEG II tumors in the primary situation
- Planned surgical treatment of esophageal carcinoma
- Possible staging advantage through FAPI PET/CT diagnostics
- Patient information and written consent
- -\> KI 60% or ECOG 0/1 (at least: self-sufficiency)
- Age ≥ 18 years
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Radiotherapy, University of Heidelberg Coordinator of this site? Confirm its status | Heidelberg | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.