NCT06408142Recruiting
Universal Test and Connect for HIV Service Delivery in South Africa
Universal Test and Connect for HIV Service Delivery in South Africa and Baltimore
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
The goal of this study is to determine how many patients with HIV or at high risk of getting HIV attend the Emergency Department (ED) in South Africa (SA). The investigators will integrate HIV assessment in the ED and see how many people who would be a candidate for a drug that prevents HIV (PrEP). Universal test and connect (UTC) is a strategy that universally tests all patients and connects patients to long-term care, whether HIV positive or negative, including referrals for PrEP. The investigator's goal is to use UTC across two busy 24-hr EDs in Cape Town, SA.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 2000 (estimated)
- First submitted
- 6 May 2024
- Start date
- 19 Jan 2026
- Primary completion date
- 1 Dec 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- HIV
- NCT number
- NCT06408142
What you commit to
- Study type: Observational
- Planned participants: 2000
- From 19 Jan 2026 to the primary completion date, 1 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients unable to provide written informed consent - i.e., have a depressed level of consciousness (head trauma or concurrent alcohol/substance abuse), determined as critically ill (triage score of "emergent"), or
Other
- do not speak a language spoken by the study team (English, Afrikaans, and Xhosa).
- In-depth interviews and surveys to providers:
- Providers who have already been interviewed (if working at both clinical sites)
- Providers who do not consent to an interview or a survey.
Who the study is looking for
- Patients attending the Emergency Department
- Ages \> or = 12 years old in South Africa
- For subset that participate in PrEP choice trial, inclusion criteria will be to ensure that they meet PrEP eligibility criteria and do not have any contraindications to PrEP (kidney disease, acute HIV signs or symptoms, already taking PrEP).
- Nurses, physicians, or advanced practice providers (APPs) who work regularly in the Emergency Department at one of the clinical sites.
- Consent to a recorded in-depth interview and/or Normalizing Process Theory (NPT) survey
Age in the registry: 12 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gugulethu Community Health Centre Coordinator of this site? Confirm its status | Cape Town | South Africa | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.