NCT06408220Recruiting
Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer
OUR Stomach Health Project: A Pilot Study to Evaluate the Feasibility of Stomach Cancer Risk Assessment for Early Detection and Secondary Prevention
Source: ClinicalTrials.gov · Last updated 13 Mar 2026
Brief summary (registry, in English)
This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach cancer. H. pylori is a bacteria that causes stomach inflammation and ulcers in the stomach. People with H. pylori infections may be more likely to develop cancer in the stomach. H. pylori breath testing can help identify the presence of H. pylori infection in a participant and help identify if the participant may be at a higher risk of developing stomach cancer. An endoscopy uses a thin, flexible lighted tube that is inserted inside the esophagus, stomach, and first part of the small intestine. This allows the doctor to see and look for abnormal areas that may need to be biopsied. Risk assessment including H. pylori evaluation, questionnaires, and endoscopies may help identify participants at high risk for stomach cancer and may be a useful screening tool for earlier stomach cancer diagnosis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 240 (estimated)
- First submitted
- 1 May 2024
- Start date
- 27 Jun 2024
- Primary completion date
- 9 Oct 2029
- Lead sponsor
- City of Hope Medical Center
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT06408220
What you commit to
- Study type: Interventional
- Planned participants: 240
- From 27 Jun 2024 to the primary completion date, 9 Oct 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of gastric cancer
- History of upper endoscopy within 2 years
Other
- Identify as Non-Hispanic White
- Known premalignant lesions of the stomach
- Women of childbearing potential: Pregnant/ nursing
- An employee who is under the direct/indirect supervision of the principal investigator (PI)/a coinvestigator/the study manager
- A direct study team member
Who the study is looking for
- Documented informed consent of the participant and/or legally authorized representative
- Assent, when appropriate, will be obtained per institutional guidelines
- Age: ≥ 40 years to ≤ 80 years
- Identify as a racial minority either Asian, Hispanic, or Black American
- Willingness to:
- Provide blood samples and undergo upper endoscopy
Age in the registry: 40 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| City of Hope Medical Center Coordinator of this site? Confirm its status | Duarte | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.