NCT06413576Completed
Homocysteine in Critically Ill Preeclampsia
The Clinical Utility of Homocysteine in Critically Ill Preeclampsia Patients
Source: ClinicalTrials.gov · Last updated 7 Apr 2026
Brief summary (registry, in English)
Preeclampsia is a disorder characterized by the new onset of hypertension and proteinuria typically presenting after 20 weeks of gestation. Elevated circulating homocysteine is a risk factor for endothelial dysfunction and vascular diseases such as atherosclerosis and occlusive disorders. Our study is to investigate the association between elevated blood homocysteine levels and complications in pregnant women in order to conclude the clinical utility of homocysteine as a marker of severity in the cases of pre-eclampsia.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 70 (actual)
- First submitted
- 6 Apr 2024
- Start date
- 19 Jan 2024
- Primary completion date
- 10 Apr 2025
- Lead sponsor
- Ain Shams University
- NCT number
- NCT06413576
What you commit to
- Study type: Observational
- Participants enrolled: 70
- From 19 Jan 2024 to the primary completion date, 10 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- On treatment with antifolate drugs such as methotrexate
Other illness
- Essential hypertension suggested by history or documentation of hypertension in pre pregnant state or hypertension before 20 weeks of gestation.
- Cardiovascular or renal failure
- Liver failure
- Diabetes mellitus
- Inflammatory or infective disorders
- History or documentation of epilepsy in prepregnant state
Other
- Space occupying lesion in brain like tuberculoma or brain tumor
- Trauma to brain
- Hyperpyrexia
Who the study is looking for
- All patients diagnosed by preeclampsia will be included in light of the following diagnostic criteria (blood pressure more than 140\\90 mm\\Hg on 2 occasions at least 4 hours apart after 20 weeks' gestation in a previously normotensive patient accompanied by Protein/creatinine ratio ≥0.3 .
Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.