NCT06414720Recruiting
Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy
Salivary MicroRNA in Endometriosis: Correlation With Progestin Treatment Response: A Prospective Observational Study
Source: ClinicalTrials.gov · Last updated 2 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to analyze the salivary miRNA specific for patients diagnosed with endometriosis, specifically evaluating the miRNA profile of patients who respond versus those who do not respond to progestin therapy. Ninety patients attending the Chronic Pelvic Pain Clinic will be recruited, and they will be asked to provide a saliva sample before starting medical therapy. The response to the therapy will be evaluated after 4 months from the beginning of the therapy itself.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 5 May 2024
- Start date
- 22 Apr 2024
- Primary completion date
- 1 Dec 2025
- Lead sponsor
- University of Udine
- Diseases
- Endometriosis
- NCT number
- NCT06414720
What you commit to
- Study type: Observational
- Planned participants: 90
- From 22 Apr 2024 to the primary completion date, 1 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently undergoing progestin therapy
Other illness
- Chronic pelvic pain syndrome with or without central sensitization assessed with the Central Sensitization Inventory Test (CSI)
- Neoplasia, diabetes, BMI \> 30 kg/m2, coagulopathies, autoimmune diseases, or other conditions that may affect salivary miRNA measurement
Other
- Pregnancy
- Pre-menarcheal or post-menopausal status
Who the study is looking for
- Age \> 18 years
- Fertile age
- Clinical-ultrasound diagnosis or histological diagnosis of endometriosis
- Informed consent
Age in the registry: 18 years to 45 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Udine Coordinator of this site? Confirm its status | Udine | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.