NCT06416488Recruiting
High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children
The Effect of High-Intensity Interval Training(HIIT) on Cardio-metabolic Indicators in School-age Children With High Cardiovascular Diseases Risk--a Randomised Intervention Trial
Source: ClinicalTrials.gov · Last updated 16 Dec 2025
Brief summary (registry, in English)
This study aims to evaluate the health promotion effects of high-intensity interval training (HIIT) intervention on school-age children who are at high risk for cardiovascular disease (CVD), as well as the long-term adherence and acceptability of HIIT in this population for future application.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 336 (estimated)
- First submitted
- 9 May 2024
- Start date
- 13 Jul 2024
- Primary completion date
- Sept 2027
- Lead sponsor
- Children's Hospital of Fudan University
- Diseases
- Obesity
- NCT number
- NCT06416488
What you commit to
- Study type: Interventional
- Planned participants: 336
- From 13 Jul 2024 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previously diagnosed with heart failure, severe malnutrition, immune deficiency, liver or kidney disease, cancer, or other diseases deemed unsuitable for participation.
- Taking weight loss drugs, or undergone weight loss surgery.
Other illness
- Secondary obesity, such as neuropsychiatric disorders, endocrine disorders, sleep apnea syndrome, or other conditions.
- Unable to take interventions due to health conditions, such as joint diseases, fractures, injuries.
Other
- Attending behavior-based intervention programs (exercise or diet) within a year.
- Regular HIIT (at least once per week).
- Other situations unsuitable for participation.
Who the study is looking for
- Aged 7-18 years at baseline.
- At least one of the following cardio-metabolic abnormalities:
- Prediabetes (Impaired fasting glucose: 5.6 ≤ fasting blood glucose level ≤ 6.9 mmol/L; or Impaired glucose tolerance: 7.8 ≤ blood glucose level after 2 hours postprandial ≤ 11.0 mmol/L).
- Lipid abnormalities (High-density lipoprotein cholesterol ≤ 1.04 mmol/L; or Low-density lipoprotein cholesterol ≥ 3.37 mmol/L; or Triglycerides ≥ 1.70 mmol/L, or Total cholesterol ≥ 5.18 mmol/L).
- Elevated blood pressure (Systolic/diastolic blood pressure consistently higher than the 90th percentile for gender, age, and height; or systolic/diastolic blood pressure ≥ 120/80 mmHg).
- Written consent from participants and their guardians.
Age in the registry: 7 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital Of Fudan University Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.