NCT06418698Recruiting
The Correlation of Intracranial Artery Calcification and Outcomes of Mechanical Thrombectomy
The Prediction of Intracranial Artery Calcification on Adverse Outcomes of Large Vessel Occlusive, Acute Ischemic Stroke Patients After Mechanical Thrombectomy: A Prospective Cohort, Observational Study
Source: ClinicalTrials.gov · Last updated 28 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
CAIS-MT is a single-center, prospective cohort study, to evaluate the correlation between outcomes of endovascular treatment(EVT) and intracranial artery calcification(IAC) in patients with acute ischemic stroke due to large or medium vessel occlusion.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 434 (estimated)
- First submitted
- 6 Apr 2024
- Start date
- 28 Mar 2024
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Zhujiang Hospital
- Diseases
- Stroke
- NCT number
- NCT06418698
What you commit to
- Study type: Observational
- Planned participants: 434
- From 28 Mar 2024 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous cerebrovascular intervention treatment or craniotomy.
Other illness
- Acute ischemic stroke occurs over 24 hours of time last known well.
- Neurologic deficits caused by diagnoses other than ischemic stroke, such as intracerebral hemorrhage, subarachnoid hemorrhage, or intracranial tumors.
Lab values
- With other underlying factors leading to IAC, such as hyperthyroidism, end-stage renal disease, long-term oral intake of vitamin K antagonist(Warfarin), chronic vitamin D deficiency or overdose, persistent hypomagnesemia, persistent hypercalcemia, persistent hyperphosphatemia and high oral calcium intake.
- Severe renal insufficiency (estimated glomerular filtration rate \< 30ml/min or serum creatinine \> 220μmol/L (2.5mg/dl)).
Other
- Lack of non-contract CT images on admission and significant artifacts in CT images preventing IAC measurement.
Who the study is looking for
- Male or non-pregnant women with acute stroke symptoms aged over 18 years.
- Occlusion of the intracranial internal carotid artery, the middle cerebral artery, the anterior cerebral artery, the posterior cerebral artery, basilar artery and intracranial vertebral artery confirmed by CT, MR angiography, or digital subtraction angiography.
- No absolute contraindication to iodinated contrast media.
- Planned treatment with EVT by clinical care team.
- Informed consent obtained from patients or their legal representatives.
- Willing to be followed up as required by the clinical study protocol.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zhujiang Hospital, Southern Medical University Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.