NCT06428097RecruitingPhase 1
Levothyroxine Supplementation for Heart Transplant Recipients
Levothyroxine Supplementation for Heart Transplant Recipients: A Randomized Control Trial
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
This will be a prospective, randomized study performed at a single tertiary referral academic medical center (University of California San Francisco, CA), evaluating the survival benefits of levothyroxine compared with no levothyroxine for patients who have undergone heart transplant. It will be double-blinded and placebo-control; participants will be randomized to receive levothyroxine or receive no levothyroxine.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 97 (estimated)
- First submitted
- 3 May 2024
- Start date
- 29 Mar 2024
- Primary completion date
- 1 Mar 2027
- Lead sponsor
- University of California, San Francisco
- NCT number
- NCT06428097
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 97
- From 29 Mar 2024 to the primary completion date, 1 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients participating in another study evaluating an investigational drug within the past 30 days.
Other illness
- Patients with pre-existing thyroid related condition including hypothyroidism, hyperthyroidism and malignancy
- Patients with a known allergy or intolerance to levothyroxine
Who the study is looking for
- Participants must be listed for heart transplantation
- Age ≥18 years
- Ability to understand and the willingness to sign a written informed consent document.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.