NCT06428721Recruiting
The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
Source: ClinicalTrials.gov · Last updated 16 Jul 2026
Brief summary (registry, in English)
The purpose of this study is to determine if the Fractionated Laser Resurfacing (FLR) procedure can protect one forearm/wrist from precancerous actinic keratosis (AKs) as well as prevent skin cancer in older subjects with active AKs. This study builds on a similar study ongoing at the Dayton Veterans Administration dermatology clinic. This study is also testing if a photograph of the skin can be used to predict where the AKs and an skin cancers will form.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 20 May 2024
- Start date
- 20 Mar 2024
- Primary completion date
- Dec 2031
- Lead sponsor
- Wright State University
- Diseases
- Melanoma
- NCT number
- NCT06428721
What you commit to
- Study type: Interventional
- Planned participants: 80
- From 20 Mar 2024 to the primary completion date, Dec 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent (within 1 year) field therapies such as efudex cream or PDT to forearms/wrists.
Other illness
- Medical history of diabetes
- History of poor wound healing or scarring
- Other serious health issues and other skin diseases that could interfere with the study
- Subjects with allergies to xylocaine will be excluded if they need this topical anesthetic.
Other
- More than 10 AKs on an extremity
- AKs that are large (2-3+, hyperkeratotic grade 3 lesions)
- AKs that are very thick (\>3 mm)
- Large tattoos that can interfere with study
- Planning to leave region in next 5 years
Who the study is looking for
- Adult Males and Females aged 60 and older
- Have at least 5 AKs on each forearm/wrist, but no more than 10 to allow for easy monitoring
- Skin type fair (Fitzpatrick I-II)
- Females must be post-menopausal and not be on systemic hormone replacement therapy
- Able to comprehend procedures and risks
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Wright State Physicians Coordinator of this site? Confirm its status | Fairborn | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.