NCT06432478Recruiting
3D Printed Custom Applicators for HDR BT (DISCO)
Study of 3D-printed Custom Applicators for Intracavitary HDR Gynaecological Brachytherapy (DISCO)
Source: ClinicalTrials.gov · Last updated 6 Feb 2026
Brief summary (registry, in English)
Intracavitary brachytherapy for gynaecological cancer currently use cylinder-type applicators or custom wax moulds to place a radioactive source in close proximity to the treatment area and provide highly conformal dose distributions. This study is a Phase IIa non-randomised interventional pilot trial that will investigate the feasibility of successfully treating patients with 3D-printed custom applicators.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 11 Jan 2024
- Start date
- 24 Nov 2023
- Primary completion date
- Sept 2028
- Lead sponsor
- Royal North Shore Hospital
- Diseases
- Endometrial cancer
- NCT number
- NCT06432478
What you commit to
- Study type: Interventional
- Planned participants: 10
- From 24 Nov 2023 to the primary completion date, Sept 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Renal transplant/horseshoe kidney
- Patients requiring interstitial brachytherapy implants
Other illness
- Inflammatory bowel disease/history of adhesions/bowel obstruction
Other
- Pregnancy
- Patients contraindicated for brachytherapy
- Patients with significant LVSI or pelvic sidewall invasion
Who the study is looking for
- Able to give informed consent
- Patients indicated for intracavitary brachytherapy
- FIGO stage I-IVA
- ECOG 0-2
- Primary endometrial cancer, primary vaginal cancer, primary vulva cancer, recurrent gynaecological cancer
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal North Shore Hospital Coordinator of this site? Confirm its status | St Leonards | Australia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.