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NCT06432686Not yet recruiting

Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS

Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS - a Pilot Study

Source: ClinicalTrials.gov · Last updated 10 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis. However, extensive use of TENS in a clinical setting is hindered by a lack of neurophysiological understanding of the effects of TENS. The primary objective of this pilot study is therefore to investigate the effects of TENS on brain activity in pwMS measured with fMRI.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
30 (estimated)
First submitted
22 May 2024
Start date
1 Oct 2025
Primary completion date
31 Dec 2025
Lead sponsor
University Medical Center Groningen
NCT number
NCT06432686

What you commit to

  • Study type: Interventional
  • Planned participants: 30
  • From 1 Oct 2025 to the primary completion date, 31 Dec 2025
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • metal or electrical implants

Other illness

  • having a psychiatric disorder
  • having a neurological disorder other than MS
  • having cardiac arrhythmia

Other

  • BMI \> 40
  • claustrophobia
  • being pregnant
  • having cognitive or communication problems which reduces the capacity to understand instructions

Who the study is looking for

  • age: 18-65 years
  • EDSS score \< 7

Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.