NCT06437639CompletedPhase 4
MEXIDOL® Sequential Therapy of Patients With Primary Open-angle Glaucoma (POAG)
Prospective, Open, Comparative, Randomized Study of the Efficacy and Safety Evaluation of the Mexidol® Sequential Therapy of Patients With Primary Open-angle Glaucoma (POAG)
Source: ClinicalTrials.gov · Last updated 12 Dec 2025
Brief summary (registry, in English)
Hypothesis: The use of neurocytoprotectors helps restore the functional activity of mitochondria, improve the nervous activity of the retina and optic nerve, and stabilize the glaucomatous process.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 24 May 2024
- Start date
- 15 Sept 2023
- Primary completion date
- 29 Nov 2023
- Lead sponsor
- Pharmasoft
- Diseases
- Glaucoma
- NCT number
- NCT06437639
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 80
- From 15 Sept 2023 to the primary completion date, 29 Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Decompensation of concomitant somatic diseases
- Taking antioxidants/nootropic drugs 6 months before inclusion in the study
Other illness
- Degenerative diseases of the central nervous system, diabetes mellitus
- A history of surgical interventions and damage to the organ of vision
- Acute or chronic inflammatory or hereditary degenerative eye diseases (anterior and posterior sections)
- Hypersensitivity to ethylmethylhydroxypyridine succinate or to any of the excipients
Other
- Primary mitochondrial dysfunction
Who the study is looking for
- An advanced stage of POAG in one or two eyes
- Hypotonic-compensated intraocular pressure (IOP)
Age in the registry: 50 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tyumen Scientific Center of the Russian Academy of Sciences Coordinator of this site? Confirm its status | Tyumen | Russia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.