NCT06440174Recruiting
Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)
Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE): a Multi-methods Study
Source: ClinicalTrials.gov · Last updated 30 Apr 2026
Brief summary (registry, in English)
This is an observational trial that will look at patients undergoing endoscopic ultrasound (EUS) in patients with oesophageal cancer and to determine the proportion of cases in which EUS changes disease management in these patients.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 160 (estimated)
- First submitted
- 8 May 2024
- Start date
- 27 Jun 2024
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- University Hospital Southampton NHS Foundation Trust
- NCT number
- NCT06440174
What you commit to
- Study type: Observational
- Planned participants: 160
- From 27 Jun 2024 to the primary completion date, 30 Jun 2026
- 14 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous oesophagectomy or oesophageal radiotherapy
- Concurrent malignancy e.g., second primary tumour
Other illness
- Recurrent or residual disease
- Distant metastatic disease detected before EUS.
Other
- Unable to undergo EUS examination.
- Other histopathological cell type
Who the study is looking for
- Patients aged 16 or above with first diagnosis of biopsy-confirmed oesophageal cancer.
- Referred for EUS examination as part of standard of care investigations.
- Tumour location in the oesophagus, or gastro-oesophageal junction (Siewert types I-III)
- MDT decision that patient is potentially curable with radical treatment (e.g., endoscopic treatment, surgery +/- neoadjuvant therapy, or definitive chemoradiotherapy)
- Prior staging with CT and PET-CT
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2
- Clinical staging of T1-T4, N0-N3, M0 disease
- Adenocarcinoma or squamous cell carcinoma (SCC) histopathological cell type
Age in the registry: 16 years to - · Sex: All · Does not accept healthy volunteers
Sites (14)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cwm Taf UHB Coordinator of this site? Confirm its status | Abercynon | United Kingdom | Recruiting |
| Royal Bournemouth Hospital Coordinator of this site? Confirm its status | Bournemouth | United Kingdom | Terminated |
| Cambridge University NHS Foundation Trust Coordinator of this site? Confirm its status | Cambridge | United Kingdom | Recruiting |
| Cardiff and Vale UHB Coordinator of this site? Confirm its status | Cardiff | United Kingdom | Recruiting |
| Velindre University NHS Trust Coordinator of this site? Confirm its status | Cardiff | United Kingdom | Recruiting |
| Glasgow Royal Infirmary Coordinator of this site? Confirm its status | Glasgow | United Kingdom | Recruiting |
| Castle Hill Hospital Coordinator of this site? Confirm its status | Hull | United Kingdom | Recruiting |
| Guy's and St Thomas' NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Imperial College Healthcare NHS Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Queen's Medical Centre, Nottingham Coordinator of this site? Confirm its status | Nottingham | United Kingdom | Recruiting |
| Salford Royal Hospital Coordinator of this site? Confirm its status | Salford | United Kingdom | Recruiting |
| University Hospital Southampton Coordinator of this site? Confirm its status | Southampton | United Kingdom | Recruiting |
| Singleton Hospital, Swansea Coordinator of this site? Confirm its status | Swansea | United Kingdom | Recruiting |
| Royal Cornwall Hospital Coordinator of this site? Confirm its status | Truro | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.