NCT06442163Completed
Average Volume-assured Pressure Support as Rescue Therapy in Obesity Hypoventilation Syndrome
Outcome Measures of Auto-titrating Average Volume-assured Pressure Support (AVAPS) as Rescue Therapy After CPAP Titration Failure in Patients With Obesity Hypoventilation Syndrome: Adherence and Sleep Quality
Source: ClinicalTrials.gov · Last updated 4 Jun 2024
Brief summary (registry, in English)
It remains unclear whether CPAP therapy should be prescribed if significant hypoxemia persists during CPAP titration, despite optimization of upper airway obstructive events, if maximum CPAP pressure is reached. The goal was to examine the effects of 6 months of home AVAPS therapy in patients with obesity hypoventilation syndrome as a potential option for patients who failed CPAP titration due to persistent hypoxemia.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 18 May 2024
- Start date
- 12 May 2020
- Primary completion date
- 30 Apr 2024
- Lead sponsor
- Assiut University
- Diseases
- Obesity
- NCT number
- NCT06442163
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 12 May 2020 to the primary completion date, 30 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with evidence of acute respiratory failure (patients with worsening symptoms during the last 2 weeks before the screening visit, a breathing frequency of 30 breaths/ minute, or signs of respiratory infections)
- Patients who had received any other form of ventilatory support before hospital admission were also excluded from the study
Other
- Patients who had been intubated during the last 3 months
Who the study is looking for
- All Clinically stable OHS patients with
- Body mass index of 30 kg/m2 ,
- Daytime hypercapnia (PaCO2 \>45 mm Hg) who had failed to respond to CPAP therapy
- had no other cause for their chronic respiratory failure and were naive to any PAP therapy.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assuit University Hospital Coordinator of this site? Confirm its status | Asyut | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.