NCT06442176Completed
Choroid In Coronary Artery Disease
Choroid Thickness May Shed Light On Early Coronary Artery Disease
Source: ClinicalTrials.gov · Last updated 4 Jun 2024
Brief summary (registry, in English)
Purpose: To investigate any relationship between choroid thickness (CTh) and coronary artery disease (CAD), particularly in its earlier stages before clinically evident. Design: Retrospective, cross-sectional observational study Methods: Setting: The study was performed in two institutions; patients were recruited in Balikesir City Hospital. The ophthalmological examinations and coronary angiograms were performed in Balikesir City Hospital. The analysis of the coronary angiograms including Gensini scoring were conducted in Bursa Education and Research Hospital. Study Population: The study group comprised 68 patients with documented CAD and 60 healthy control subjects. Patients with high myopia, cataracts, retinal vascular disease, retinal surgery, retinal dystrophy, laser photocoagulation, intravitreal anti-VEGF treatment, glaucoma, uveitis, retinal disorders, any systemic diseases were excluded from the study groups. Observation Procedure: Refractive examination, corrected visual acuity, intraocular pressure measurements, anterior and posterior segment examinations. Following measurements of macular thickness and retinal nerve fiber layer, choroidal thickness of both eyes was assessed by enhanced depth imaging optical coherence tomography.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 128 (actual)
- First submitted
- 27 May 2024
- Start date
- 1 Mar 2021
- Primary completion date
- 1 Mar 2023
- Lead sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT06442176
What you commit to
- Study type: Observational
- Participants enrolled: 128
- From 1 Mar 2021 to the primary completion date, 1 Mar 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Retinal surgery
Other illness
- Retinal vascular disease
- Any systemic diseases
Age
- Retinal disorders (comprising diabetic macular edema, diabetic/hypertensive retinopathy, vein occlusions, retinal dystrophy, epiretinal membrane, vitreomacular traction, age-related macular degeneration)
Other
- High myopia (\> 6D)
- Cataracts
- Retinal dystrophy
- Laser photocoagulation
- Intravitreal anti-VEGF treatment
- Glaucoma
- Uveitis
- Obesity (body-mass index ≥30 kg/m²)
Who the study is looking for
- Normal coronaries at coronary angiography for healthy control group
- Without any coronary artery disease equivalent diseases such as peripheral artery disease, cerebrovascular disease and stroke for healthy control group
- Ability to give informed consent for the study
- Coronary artery disease with stenosis detected in coronary angiogram for coronary artery disease group
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Balikesir City Hospital Coordinator of this site? Confirm its status | Balıkesir | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.