NCT06449989Recruiting
Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
GENCONCOR-1 study is translational research aimed to investigate the concordance of the molecular genetic profile of the primary tumor and brain metastases (BM) of colorectal cancer (CRC). The study was conducted by post hoc analysis of pairs of samples of histological material with determination of the mutational status of genes KRAS, NRAS, BRAF, HER2 and MSI.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 30 (estimated)
- First submitted
- 4 Jun 2024
- Start date
- 1 Apr 2024
- Primary completion date
- Sept 2027
- Lead sponsor
- Blokhin's Russian Cancer Research Center
- Diseases
- Colorectal cancer
- NCT number
- NCT06449989
What you commit to
- Study type: Observational
- Planned participants: 30
- From 1 Apr 2024 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Missing one sample from a pair of tumor samples.
- Low quality or lack of tumor material for molecular genetic research.
Who the study is looking for
- Men and women over 18 years of age.
- Histologically confirmed cancer of the colon or rectum.
- Histologically confirmed metastatic lesion of the brain.
- Neurosurgical resection for brain metastases of colorectal cancer.
- Presence of paired tumor samples (both primary tumor and intracranial material).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Blokhin's Russian Cancer Research Center Coordinator of this site? Confirm its status | Moscow | Russia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.