NCT06451341Active, not recruiting
IMplementation of CAB+RPV LA for People With HIV in Non-Metropolitan Areas
IMplementation of CAB+RPV LA for People With HIV in Non-Metropolitan Areas: Addressing Adherence Barriers Through Learning and Evidence-Informed Strategies (IM-CAPABLE)
Source: ClinicalTrials.gov · Last updated 24 Jul 2026
Brief summary (registry, in English)
The goal of this implementation science study is to learn about the experience of receiving and providing cabotegravir + rilpivirine long-acting (CAB+RPV LA) injections as treatment for human immunodeficiency virus (HIV) for people who live a significant distance from an HIV provider. The main questions it aims to answer are: * Is CAB+RPV LA feasible and acceptable to patients and staff? * What barriers and supports exist and have the most impact on receiving and providing CAB+RPV LA? * How does CAB+RPV LA affect HIV stigma, treatment satisfaction, medication adherence and viral suppression? People living with HIV who reside outside of the Omaha, Nebraska metro area and are starting CAB+RPV LA as part of regular medical care for HIV will be invited to participate in this study which involves completing questionnaires and an interview over 15 months. Clinic staff who are involved in providing HIV care and CAB+RPV LA will also provide input through questionnaires and interviews.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 75 (estimated)
- First submitted
- 20 May 2024
- Start date
- 1 Jul 2024
- Primary completion date
- May 2028
- Lead sponsor
- University of Nebraska
- Diseases
- HIV
- NCT number
- NCT06451341
What you commit to
- Study type: Observational
- Planned participants: 75
- From 1 Jul 2024 to the primary completion date, May 2028
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Patient Inclusion Criteria:
- Age ≥ 19 years old (as per Nebraska's adult age definition) with documented HIV infection
- Receiving care for the management of HIV disease by a provider at the Nebraska Medicine/UNMC Specialty Care Center ( UNMC SCC)
- Deemed a clinically eligible candidate for CAB+RPV LA per HIV treatment guidelines and through shared medical decision-making by provider and patient
- Resides outside of the Omaha, Nebraska metropolitan area
- Patient Exclusion Criteria:
- Does not meet the clinical guidelines eligibility criteria for CAB+RPV LA
- Currently receiving CAB+RPV LA
- Currently incarcerated
- Unable to give informed consent for participation
- Pregnant or planning to become pregnant during the study period
- Intends to move from their current residence to the Omaha metropolitan area or intend to move out of the Specialty Care Center service area within 12 months after enrollment
- Staff Inclusion Criteria:
- Age ≥ 19 years old (as per Nebraska's adult age definition)
- Staff member of the UNMC SCC, the Nebraska Medicine Grand Island Clinic, the Myrtue Medical Center, or the Shenandoah Medical Center who is providing HIV-related care to patients and has a dedicated role in the IM-CAPABLE study
- Able to provide written and/or oral feedback as outlined in the implementation method
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nebraska Medicine Grand Island Clinic Coordinator of this site? Confirm its status | Grand Island | United States | Unknown status |
| Myrtue Medical Center Coordinator of this site? Confirm its status | Harlan | United States | Unknown status |
| University of Nebraska Specialty Care Center Coordinator of this site? Confirm its status | Omaha | United States | Unknown status |
| Shenandoah Medical Center Coordinator of this site? Confirm its status | Shenandoah | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.