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NCT06452745Recruiting

Early Diagnosis of Colorectal Cancer Based on a Non-invasive Metabolomics Profile

Source: ClinicalTrials.gov · Last updated 2 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Colorectal cancer is the most frequent tumor in our environment if both sexes are considered together. Every year almost 800 cases are diagnosed in the districts of Tarragona. A little more than half of colorectal cancers are cured with surgery, with or without the addition of complementary treatments with chemotherapy and/or radiation therapy. Those who are not cured is because at the time of diagnosis the disease has already spread or they spread after having been treated surgically with curative intent. The purpose of the EarlyCRC project is to determine whether metabolites (substances of low molecular weight) can be found in the urine and stool of patients with colorectal cancer or polyps that can be easily and cheaply differentiated (urine or stool analysis) between the patients affected by colorectal cancer or polyps, from healthy individuals. For the identification of these possible metabolites, the urine analysis will be performed using the usual techniques in metabolomics, which studies the existing metabolites in biological processes.

Status (registry)
Recruiting
Study type
Observational
Enrollment
2000 (estimated)
First submitted
5 Jun 2024
Start date
20 Jul 2019
Primary completion date
30 Jun 2030
Lead sponsor
Institut Investigacio Sanitaria Pere Virgili
NCT number
NCT06452745

What you commit to

  • Study type: Observational
  • Planned participants: 2000
  • From 20 Jul 2019 to the primary completion date, 30 Jun 2030
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Patients diagnosed with another primary neoplasm in the last 5 years, with the exception of carcinoma in situ of the cervix or non-melanoma skin cancer.
  • Patients with severe active liver disease (hepatitis, cirrhosis).

Lab values

  • Patients with severe kidney disease stage IV (creatinine clearance \< 30 ml/min).

Other

  • Refusal to sign informed consent.

Who the study is looking for

  • Patients with a positive FOBT test result from the Colorectal Cancer Early Detection Program and referred for a colonoscopy.

Age in the registry: 50 years to 70 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hospital Universitari Sant Joan de Reus
Coordinator of this site? Confirm its status
ReusSpainRecruiting
Hospital Universitari Joan XXIII
Coordinator of this site? Confirm its status
TarragonaSpainRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.