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NCT06455189WithdrawnPhase 1

Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas

Source: ClinicalTrials.gov · Last updated 1 Jul 2026

Brief summary (registry, in English)

Magnetic resonance imaging, MRI, is a procedure that uses radio waves, a powerful magnet, and a computer to make a series of detailed pictures of areas inside the body. The goal of this study is to determine if MR fingerprinting, new way of acquiring MRI images, can help identify the extent of tumor spread in the brain, better than routine MRI images.

Status (registry)
Withdrawn
Phase (registry)
Phase 1
Study type
Interventional
Enrollment
0 (actual)
First submitted
7 Jun 2024
Start date
Dec 2025
Primary completion date
1 Jun 2029
Lead sponsor
Case Comprehensive Cancer Center
Diseases
Glioblastoma
NCT number
NCT06455189

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Contraindication to surgical treatment
  • Prior treatment for glioblastoma
    • Stage II:
  • Participants undergoing only stereotactic biopsy or less than gross total resection
  • Previously treated/ recurrent glioma.

Other

  • Contraindications to MRI
  • Inability to undergo MRI imaging
  • Participants undergoing LITT
  • Inability to consent for the study

Who the study is looking for

  • Age > 18
  • MR imaging findings suggestive of GB
  • Maximal tumor diameter greater than 3 cm
  • Ability to provide written informed consent
  • Ability to undergo MRI scan
  • Consideration for biopsy, subtotal or gross total resection.
  • Age > 18
  • MR imaging findings suggestive of GB
  • Maximal tumor diameter greater than 3 cm
  • Ability to provide written informed consent
  • Ability to undergo MRI scan
  • Lesions amenable to gross total resection
  • Presence of peritumoral FLAIR signal abnormality beyond the area of enhancement.

Criteria the registry did not label

  • Stage I:

Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
University Hospitals Cleveland Medical Center, UH Department of Radiology, Case Comprehensive Cancer Center
Coordinator of this site? Confirm its status		ClevelandUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.