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NCT06455371Recruiting

Patient-centered Dosage of Levothyroxine

Patient-centered Decision Support Tool for Levothyroxine Dosage

Source: ClinicalTrials.gov · Last updated 10 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Levothyroxine is the most used thyroid hormone replacement when the thyroid gland is failing. Because dosage adjustment normally takes several months, the investigators have developed a decision support tool (DST) that predicts optimal dosage based on repeated blood samples the first 2 weeks after initiation of therapy. In this randomized study the investigators will include patients that start levothyroxine therapy after total thyroidectomy. The use of DST to advice the physician about an early dosage adjustment will be compared with common clinical practice, that is dosage adjustment every 2 months. The effect of DST use will be assessed by studying the possible relationship between fast optimal dose adjustment, patient reported outcome measures, and ability to work.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
240 (estimated)
First submitted
10 Jan 2024
Start date
20 Dec 2024
Primary completion date
Dec 2026
Lead sponsor
University Hospital of North Norway
NCT number
NCT06455371

What you commit to

  • Study type: Interventional
  • Planned participants: 240
  • From 20 Dec 2024 to the primary completion date, Dec 2026
  • 3 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Anaplastic thyroid cancer, thyroid cancer with distant metastasis, graves disease, toxic nodules, pregnancy

Who the study is looking for

  • Total or completion thyroidectomy for differentiated thyroid cancer og benign thyroid nodules at Norwegian hospitals

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (3)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Haukeland University Hospital
Coordinator of this site? Confirm its status
BergenNorwayRecruiting
Oslo University Hospital
Coordinator of this site? Confirm its status
OsloNorwayRecruiting
University Hospital of North Norway
Coordinator of this site? Confirm its status
TromsøNorwayRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.