NCT06455683Not yet recruiting
The A D A G I O Study
The Effect of Glaucoma Surgery on Aqueous Dynamics in Patients With Glaucoma or Ocular Hypertension
Source: ClinicalTrials.gov · Last updated 12 Jun 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to investigate the effect of different types of glaucoma surgery on aqueous dynamics parameters (IOP, aqueous flow rate, trabecular outflow facility and uveoscleral outflow) in patients with uncontrolled open angle glaucoma or ocular hypertension (OHT)
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 28 May 2024
- Start date
- Jun 2024
- Primary completion date
- Jun 2029
- Lead sponsor
- Guy's and St Thomas' NHS Foundation Trust
- Diseases
- Glaucoma, High blood pressure
- NCT number
- NCT06455683
What you commit to
- Study type: Observational
- Planned participants: 150
- From Jun 2024 to the primary completion date, Jun 2029
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- It is judged as not clinically safe or patient is not willing to undergo treatment washout (stop taking glaucoma drops).
- Current use of any investigational drug or device or current participation in an interventional clinical trial/study.
Other illness
- Allergy to fluorescein.
Other
- Diagnostic criteria for inclusion not met.
- Participants in the study must be able to understand English to complete some of the tests so those who might not adequately understand written information or verbal explanations in English will not be included
Who the study is looking for
- Males or females between the ages of 18 and 90 (inclusive).
- Able to understand the study and give informed consent.
- Willing, able and available to participate in the study. If Flurophotometer test required must not have had prior cataract surgery.
- Diagnosis of glaucoma or OHT which requires glaucoma surgery (trans-trabecular meshwork surgery with or without an implant, trans-scleral surgery with or without implant, ciliary body treatment, suprachoroidal surgery with or without implant, external non-incisional treatment). (Defined as primary or secondary glaucoma; all types of secondary glaucoma may be included. Glaucoma will be diagnosed based on abnormal visual field testing and corresponding disc changes once seen by a glaucoma specialist.)
- It is judged clinically safe for the patient to undergo treatment washout (stop taking glaucoma drops).
Age in the registry: 18 years to 90 years · Sex: All
This page is information, not medical advice. Discuss any trial with your doctor.