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NCT06455878Recruiting

Mobile Applet for Weight Management in Obese Heart Failure Patients

The Impact of Dietary Management Applet for Weight Reduction in Obese Heart Failure Patients: a Multicenter, Single-blind Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 27 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart failure. The main questions are: Does the use of a diet management APP and intelligent weight scale reduce 1-year all-cause mortality, heart failure hospitalization, and first heart failure hospital stay? Does the use of a diet management APP and intelligent weight scale improve the outcomes of assessment of heart failure frailty and quality of life for heart failure? Researchers will compare using the fully functional diet management app and intelligent weight scale to using the limitedly functional app and intelligent weight scale to see if the app works to improve heart failure conditions. Participants will: Use the diet management app at every meal and the intelligent weight scale every day for 12 months, and visit the clinic at 12 months for checkups.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
830 (estimated)
First submitted
3 Jun 2024
Start date
6 Jun 2024
Primary completion date
30 Jun 2026
Lead sponsor
Heart Health Research Center
NCT number
NCT06455878

What you commit to

  • Study type: Interventional
  • Planned participants: 830
  • From 6 Jun 2024 to the primary completion date, 30 Jun 2026
  • 26 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Current use of weight-loss medications or planned bariatric surgery;
  • Concurrent participation in another interventional clinical study.

Other illness

  • End-stage heart failure (≥2 hospitalizations for heart failure in the past 3 months, intolerance to guideline-directed medical therapy (GDMT), or dependence on inotropic agents);
  • Heart failure with reversible causes (e.g., peripartum cardiomyopathy, fulminant myocarditis);
  • Uncontrolled thyroid disease (hyperthyroidism/hypothyroidism) or end-stage liver failure;
  • Malignancy with an expected survival \<1 year;
  • Conditions potentially hindering protocol compliance, as judged by the investigator (e.g., habitual reliance on food delivery services or company cafeteria meals);

Lab values

  • Moderate or severe anemia (hemoglobin \[Hb\] \<90 g/L);
  • Renal insufficiency (estimated glomerular filtration rate \[eGFR\] \<30 mL/min/1.73 m²) or ongoing dialysis;

Other

  • Alcohol or substance abuse;
  • Planned hospitalization during the trial period;

Who the study is looking for

  • Age ≥18 years;
  • Left ventricular ejection fraction (LVEF) ≤ 50%, with New York Heart Association (NYHA) class II-III;
  • Body mass index (BMI) ≥ 26 kg/m² or male waist-to-hip ratio (WHR=waist circumference/hip circumference) ≥ 0.9, female waist-to-hip ratio ≥ 0.85;
  • Ability to use a smartphone and demonstrate compliance via a diet management mobile application during a 2-week ±1-week run-in period;
  • History of heart failure hospitalization within the past 6 months;
  • Signed informed consent.

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (26)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Xiu Yan Manchu Autonomous County Central People's Hospital
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AnshanChinaRecruiting
Emergency General Hospital
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BeijingChinaNot yet recruiting
Beijing Fangshan District First Hospital
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BeijingChinaRecruiting
Beijing Anzhen Hospital
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BeijingChinaRecruiting
Beijing Chuiyangliu Hospital
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BeijingChinaNot yet recruiting
Qin Yuan County People's Hospital
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ChangzhiChinaRecruiting
Tiemei General Hospital of Liaoning Health Industry Group
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DiaobingshancunChinaNot yet recruiting
Guangzhou Red Cross Hospital
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GuangzhouChinaRecruiting
Jixi City People's Hospital
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JixiChinaRecruiting
Kaifeng Central Hospital
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KaifengChinaNot yet recruiting
Langfang People's Hospital
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LangfangChinaRecruiting
Ruyang County People's Hospital
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LuoyangChinaRecruiting
Luoyang No.6 People's Hospital
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LuoyangChinaRecruiting
Pingdu People's Hospital
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PingduChinaRecruiting
Ningling County People's Hospital
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ShangqiuChinaRecruiting
Yongcheng People's Hospital
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ShangqiuChinaRecruiting
Shenyang Tenth Hospital
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ShenyangChinaRecruiting
Taian First Hospital
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TaianChinaRecruiting
Yuhuan Second People's Hospital
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TaizhouChinaNot yet recruiting
Tongliao People's Hospital
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TongliaoChinaRecruiting
The First Affiliated Hospital of Xinjiang Medical University
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ÜrümqiChinaRecruiting
Weihai Central Hospital
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WeihaiChinaNot yet recruiting
Xian Red Cross Hospital
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XianChinaRecruiting
Shangcheng County People's Hospital
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XinyangChinaRecruiting
The First Affiliated Hospital of Xi'an Jiaotong University, Yulin Branch Hospital
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YulinChinaRecruiting
Henan Provincial Chest Hospital
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ZhengzhouChinaNot yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.