NCT06460077Enrolling by invitation
Exploring Pathology Related to Slowly Expanding Lesions Using Advanced Imaging
Source: ClinicalTrials.gov · Last updated 16 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is an open, follow-up study to compare the performance of three critical imaging methods to detect chronic active lesions in Multiple Sclerosis (MS) in vivo.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 15 (estimated)
- First submitted
- 10 Jun 2024
- Start date
- 3 Oct 2024
- Primary completion date
- Jun 2028
- Lead sponsor
- Turku University Hospital
- Diseases
- Multiple sclerosis
- NCT number
- NCT06460077
What you commit to
- Study type: Observational
- Planned participants: 15
- From 3 Oct 2024 to the primary completion date, Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Corticosteroid treatment within 4 weeks of imaging
- Exposure to experimental radiation in the past 12 months such that radiodosimetry limits would be exceeded by participating in this study
- Intolerance to previous PET scans; i.e. previous hypersensitivity reactions to any PET ligand or imaging agent or failure to participate in and comply with previous PET scans
Other illness
- Patients with other neurodegenerative disease than MS
- Patients with other autoimmune disease than MS
- Patients with other significant or malignant underlying disease of any other organ system
- Patients with claustrophobia, or a history of moderate to severe anxiety disorder or panic attacks (which could potentially lead to preterm termination of the imaging)
Other
- Patients that are pregnant or breast-feeding
- Patients with significant abnormal findings other than MS in the screening MRI
- Contraindication to PET scan investigations
Who the study is looking for
- Signing the informed consent form
- MS diagnosis in accordance with McDonald 2017 criteria
- Available longitudinal brain MR images (minimum 1 year)
- Simultaneous QSM MRI sequence and TSPO-PET
- Lesions with iron rim/s
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Turku PET Centre Coordinator of this site? Confirm its status | Turku | Finland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.