NCT06465966Active, not recruiting
UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the use of ionizing-radiation photo acoustic imaging (iRAI) for proton radiation treatment.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 11 (actual)
- First submitted
- 14 Jun 2024
- Start date
- 23 Sept 2024
- Primary completion date
- 1 Sept 2027
- Lead sponsor
- University of Florida
- Diseases
- Prostate cancer
- NCT number
- NCT06465966
What you commit to
- Study type: Interventional
- Participants enrolled: 11
- From 23 Sept 2024 to the primary completion date, 1 Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- A patient with a significant medical implant or hardware in the treatment area
Other
- A patient who would not be tolerable or will feel nervous due to the sensation and coolness of the ultrasound gel appliedt to skin
- A patient may feel uncomfortable with the modular transducer arrays contacting the skin during treatment. Each transducer array contacts a 15 cm × 15 cm area of skin, and depending on the patient's abdominal size, a minimum of two and a maximum of three such areas may be in contact. This produces a sensation of light pressure on the abdomen - comparable to a light hold on the index finger - lasting for a total of 4 minutes.
Who the study is looking for
- Disease: Prostate cancer
- Treatment site:
- Prostate or prostate and seminal vesicle
- No regional lymph node is involved
- Patient's body weight: Patient's body weight is less than 350 lbs to consider the total weight limit that the ProteusONE treatment table and the robotic arm can operate
- Treatment volume size: maximum size less than 15 x 15 cm in a cross-section and a thickness less than 20 cm to consider 2D transducer matrix size
- Provision to sign the consent form and understand the non-invasiveness of iRAI
- Patient agreement on tolerance on placing a water bag to acquire iRAI during treatment
- Treatment modality: Proton radiation therapy with UFHPTI's ProteusONE gantry using PBS
Age in the registry: 18 years to 100 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Univeristy of Florida Health Proton Therapy Institute Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.