NCT06466967Completed
Clinical Utility of Tight Objectives of Advanced Hybrid Closed-loop Systems Among Type 1 Diabetes Patients (TightT1AHCL)
Clinical Utility of a Tight Glucose Objectives Through Advanced Hybrid Closed-loop Systems in Adult Patients With Type 1 Diabetes and Poor Glycemic Control
Source: ClinicalTrials.gov · Last updated 19 Mar 2026
Brief summary (registry, in English)
Diabetes is a chronic disease with a relevant public health burden. Maintaining blood glucose levels as close to normal as possible is essential to avoid the associated microvascular and macrovascular complications. Therefore, the key to prevent and/or reduce the development of these chronic complications lies in an adequate and strict glycemic control. This study consist of a prospective analytical clinical study in patients with type 1 diabetes (T1D). The main objective is to analyze the effect on time in range (TIR, 70-180 mg/dL) of interstitial glucose after switching to a tighter glucose objective in advanced hybrid closed-loop (AHCL) treated adult T1D patients previously treated with multiple dose insulin injection (MDI) or other AHCL systems without tighter glucose objective function.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 40 (actual)
- First submitted
- 14 Jun 2024
- Start date
- 15 Jun 2024
- Primary completion date
- 15 Dec 2025
- Lead sponsor
- Castilla-La Mancha Health Service
- Diseases
- Type 1 diabetes
- NCT number
- NCT06466967
What you commit to
- Study type: Observational
- Participants enrolled: 40
- From 15 Jun 2024 to the primary completion date, 15 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current or previous treatment with CamAPS-Ypsopump.
Other illness
- Other types of diabetes.
- Uncontrolled psychiatric disease.
- History of severe hypoglycemia.
Other
- Pregnancy or pre-conception control.
- No glucometric data available during the periods under study.
Who the study is looking for
- Patients with type 1 diabetes.
- Age greater than or equal to 18 years.
- HbA1c \> 7% (previous poor glycemic control condition).
- Prior treatment with MDI or aHCL.
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ciudad Real General University Hospital Coordinator of this site? Confirm its status | Ciudad Real | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.