NCT06469294Completed
Evaluation of Chlorhexidine Gel Associated with Photodynamic Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics
Source: ClinicalTrials.gov · Last updated 26 Nov 2024
Brief summary (registry, in English)
The objective of this clinical trial is to evaluate chlorhexidine gel associated with photodynamic therapy in the treatment of chronic periodontitis in Type 2 diabetics The main questions it aims to answer are: • To evaluate if the use of 2% chlorhexidine gel associated with 0.005% methylene blue and laser therapy is superior to conventional periodontal treatment associated with photodynamic therapy in Type 2 diabetics Participants will receive periodontal treatment carried out with the use of 2% chlorhexidine gel associated with 0.005% methylene blue and laser therapy, associated with conventional periodontal treatment, as well as the use of photodynamic therapy associated to conventional periodontal treatment in Type 2 diabetics patientes. So, 20 periodontitis patients will be selected. Patients will be separated in two groups; Test, use of 2% chlorhexidine gel associated with 0.005% methylene blue and laser therapy + Periodontal Disease with PD\> 5mm and Control, conventional periodontal treatment with gel control with fisiological solution + Laser therapy. Clinical parameters and microbiological parameters were evaluated at baseline and 3 months after periodontal treatment: Plaque Index, Bleeding On Probe, Probing depth, Gingival Recession and Clinical Attachment Level, and Microbiological parameters will be checked by PCR, for evaluating A.a, P.g., T.f., C.albicans.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 15 Jun 2024
- Start date
- 30 May 2024
- Primary completion date
- 7 Oct 2024
- Lead sponsor
- Universidade Federal Fluminense
- Diseases
- Type 2 diabetes
- NCT number
- NCT06469294
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 30 May 2024 to the primary completion date, 7 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- anti-inflammatories or hormone replacement therapy
- physical/emotional stress, medications that influence periodontal tissues.
Other illness
- Participants with hypersensitivity to the components of chlorhexidine gel or methylene blue and laser therapy
- Drugs ( alcoholics, anti-inflammatories and antibiotics in the last 6 months)
- Any evidence of systemic modifying factors of periodontal disease, except diabetics, and which, therefore, may directly interfere with the completion of the work. The factors described in the literature include:
Other
- osteoporosis types I and II
- acquired or induced immunosuppression
- Pregnant or lactating women
- clinical manifestations of oral candidosis
Who the study is looking for
- Participants over 18 years old
- Adults with type 2 diabetics
- Adults with periodontal disease
- Pockets with probing depth greater than 5 mm.
Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidade Federal Fluminense Coordinator of this site? Confirm its status | Nova Friburgo | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.