NCT06470243RecruitingPhase 3
Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
A Phase III Study of Cabazitaxel With or Without Carboplatin in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC), Stratified by Aggressive Variant Signature
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
This phase III trial compares the effect of adding carboplatin to the standard of care chemotherapy drug cabazitaxel versus cabazitaxel alone in treating prostate cancer that keeps growing even when the amount of testosterone in the body is reduced to very low levels (castrate-resistant) and that has spread from where it first started (primary site) to other places in the body (metastatic). Carboplatin is in a class of medications known as platinum-containing compounds. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Chemotherapy drugs, such as cabazitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Prednisone is often given together with chemotherapy drugs. Prednisone is in a class of medications called corticosteroids. It is used to reduce inflammation and lower the body's immune response to help lessen the side effects of chemotherapy drugs and to help the chemotherapy work. Giving carboplatin with the standard of care chemotherapy drug cabazitaxel may be better at treating metastatic castrate-resistant prostate cancer.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 528 (estimated)
- First submitted
- 17 Jun 2024
- Start date
- 27 Nov 2024
- Primary completion date
- 30 Jun 2029
- Lead sponsor
- SWOG Cancer Research Network
- Diseases
- Prostate cancer
- NCT number
- NCT06470243
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 528
- From 27 Nov 2024 to the primary completion date, 30 Jun 2029
- 174 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- STEP 1 SCREENING REGISTRATION: NOTE: All participants must have biopsy tissue submitted to MD Anderson Cancer Center prior to randomization for alteration assessment. Participants must have determination of their AVPC-Molecular Pathologic Signature immunohistochemistry (MSIHC) status from central assessment by the MD Anderson Clinical Pathology Laboratory using Clinical Laboratory Improvement Act (CLIA) certified immunohistochemistry (IHC) assays for TP53, RB1 and PTEN. In addition, while not mandated, CLIA certified next generation sequencing (NGS) of tumor deoxyribonucleic acid (DNA) and/or circulating tumor derived DNA (ctDNA) assessment of AVPC-MS marker status will be collected from participants for whom it is available
- STEP 1 SCREENING REGISTRATION: Participants must have a histologically confirmed diagnosis of prostate cancer at the time of step 1 registration
- STEP 1 SCREENING REGISTRATION: Participants must have castrate-resistant prostate cancer and metastatic disease by bone scan and/or CT/MRI (i.e., soft tissue, visceral, lymph node)
- STEP 1 SCREENING REGISTRATION: Participants may have received any prior therapy, but one must be docetaxel or contain docetaxel in either the castrate-sensitive and/or castrate resistant disease state
- STEP 1 SCREENING REGISTRATION: Participants must be ≥ 18 years of age at the time of step 1 screening registration
- STEP 1 SCREENING REGISTRATION: Participants must have solid tumor biopsy material (formalin-fixed paraffin-embedded (FFPE) tissue blocks and/or 10 cut slides on four-micron thick unstained positive charged slides of FFPE tissue) available for submission for alterations in TP53, RB1 and PTEN by IHC using CLIA certified assays in the MD Anderson Clinical Pathology Laboratory. This specimen is required for central assessment of the AVPC-MSIHC regardless of whether the site has already locally evaluated the AVPC-MS status
- STEP 1 SCREENING REGISTRATION: Tumor samples submitted for analysis must have been collected within 12 months prior to step 1 screening registration. Samples from metastatic lesions collected in the castrate-resistant disease state are preferable but not mandatory. Samples obtained during the hormone-naive disease state are acceptable if collected within 12 months of step 1 screening registration. If more than one tumor sample exists, the sample obtained closest to the date of registration should be submitted to MDACC for analysis
- NOTE: Sites will receive an email from Southwest Oncology Group (SWOG) Statistics and Data Management Center containing participant results of Aggressive Variant Prostate Cancer Molecular Signature (AVPC-MS) assessment within 5-12 business days after tissue submission to MD Anderson Clinical Pathology Laboratory. The participant's AVPC-MS signature result (positive or negative) is required BEFORE randomization on to step 2. If sites receive a non-evaluable AVPC-MS signature result, SWOG Statistics and Data Management Center will provide instructions for resubmission
- STEP 1 SCREENING REGISTRATION: NOTE: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
- STEP 1 SCREENING REGISTRATION: Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines. Documentation of informed consent via remote consent is allowed
- For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations
- STEP 2 RANDOMIZATION: NOTE: Participants must be registered to step 2 randomization within 70 days after registration to step 1. Participants must plan to start protocol therapy no more than 14 days after step 2 randomization
- STEP 2 RANDOMIZATION: Participants must have castrate levels of testosterone with a baseline level \< 50ng/dL within 28 days prior to step 2 randomization
- STEP 2 RANDOMIZATION: Participants must have evidence for metastatic prostate cancer by bone scan and/or CT/MRI (i.e., soft tissue, visceral, lymph node). Visceral and/or soft-tissue metastases must be ≥ 1.0 cm in diameter and lymph nodes must be \> 1.5 cm diameter in the short axis. Scans must be obtained within 28 days prior to randomization
- NOTE: All disease must be assessed and documented on the baseline/pre-registration tumor assessment form
- STEP 2 RANDOMZIATION: Participants must have progressive disease (PD) in the opinion of the treating investigator according to any of the following criteria
- Progression in measurable disease (RECIST 1.1 criteria). Patient with measurable disease must have at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded). Each lesion must be at least 10 mm when measured by computed tomography (CT) \[CT scan thickness no greater than 5 mm\] or magnetic resonance imaging (MRI). Lymph nodes should be ≥ 15 mm in short axis. Previously irradiated lesions, primary prostate lesion and bone lesions will be considered non-measurable disease
- Progression in bone as evidenced by:
- Appearance of 2 or more new bone lesions on bone scan (BS). If equivocal, they must be confirmed by other imaging modalities (CT; MRI), and/or repeat BS \> 4 weeks later
- Appearance of a new lytic lesion(s) and/or increasing size of an existing lesion by CT/MRI, since AVPC tumors may produce lytic bone lesions that are not detected on conventional bone scans
- Rising prostate-specific antigen (PSA) defined (Prostate Cancer Working Group 2 \[PCWG2\]) as at least two consecutive rises in PSA to be documented over a reference value (measure 1) taken at least one week apart. The first rising PSA (measure 2) should be taken at least 7 days after the reference value. A third confirmatory PSA measure is required (2nd beyond the reference level) to be greater than the second measure and it must be obtained at least 7 days after the 2nd measure. If this is not the case, a fourth PSA measure is required to be taken and be greater than the 2nd measure. In case of progression based on rising PSA only, the first rising PSA (measure 2) must be obtained within 6 months of initiation of androgen receptor (AR) targeted therapy (≤ 6 months)
- Clinical progression. Increasing symptoms unequivocally attributed to disease progression as judged by the treating physician
- STEP 2 RANDOMIZATION: Participants must not have received prior cabazitaxel or carboplatin
- STEP 2 RANDOMIZATION: Participants must not be receiving treatment on another therapeutic clinical trial at the time of randomization. Chemotherapies, bone targeting therapies, immunotherapies and clinical trial agents must be discontinued ≥ 21 days prior to randomization. Stereotactic radiation (SART) must be discontinued ≥ 3 days prior to randomization
- STEP 2 RANDOMIZATION: Participants must not be receiving radiation therapy or kyphoplasty-vertebroplasty within 14 days prior to randomization or major surgery (e.g., open abdominal, pelvic, thoracic, orthopedic or neurosurgery) within 28 days prior to step 2 randomization
- STEP 2 RANDOMIZATION: Participants must not have untreated fractures and/or cord compression
- STEP 2 RANDOMIZATION: Participants must not have symptomatic uncontrolled brain metastases. Properly treated brain metastases (i.e., with stereotactic radiation) within 14 days are allowed
- STEP 2 RANDOMIZATION: Participants must have Zubrod performance status of 0 - 2 within 28 days prior to step 2 randomization
- STEP 2 RANDOMIZATION: Participants must have a complete medical history and physical exam within 28 days prior to step 2 randomization
- STEP 2 RANDOMIZATION: Absolute neutrophil count ≥ 1.5 x 10\^3/uL (within 28 days prior to step 2 randomization)
- STEP 2 RANDOMIZATION: Platelets ≥ 100 x 10\^3/uL (unless clinical evidence of bone marrow infiltration by tumor in which case \> 75 x 10\^3/uL are allowed) (within 28 days prior to step 2 randomization)
- STEP 2 RANDOMIZATION: Total bilirubin ≤ institutional upper limit of normal (ULN) with the exception of isolated hyperbilirubinemia due to Gilbert's syndrome or if the participant has liver metastases and/or acute tumor associated illness \< 4x ULN (within 28 days prior to step 2 randomization)
- STEP 2 RANDOMIZATION: Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ≤ 3 × institutional ULN (or if participant has liver metastases and/or acute tumor-associated illness, ≤ 4x institutional ULN) (within 28 days prior to step 2 randomization)
- STEP 2 REGISTRATION: Participants must have a calculated creatinine clearance ≥ 30 mL/min using the Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to step 2 randomization
- STEP 2 RANDOMIZATION: Participants with peripheral neuropathy must have ≤ grade 2 peripheral neuropathy (Common Terminology Criteria for Adverse Events \[CTCAE\] version 5.0) (within 28 days prior to step 2 randomization)
- STEP 2 RANDOMIZATION: Participants who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including vasectomy with testing showing no sperm in the semen
- STEP 2 RANDOMIZATION: Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the treatment regimen
- STEP 2 RANDOMIZATION: Participants with known human immunodeficiency virus (HIV)-infection must be on effective anti-retroviral therapy at registration and have undetectable viral load test on the most recent test results obtained within 6 months prior to registration
- STEP 2 RANDOMIZATION: Participants must be offered the opportunity to participate in specimen banking. With participant consent, specimens must be collected and submitted via the SWOG Specimen Tracking System
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (174)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lehigh Valley Hospital-Cedar Crest Coordinator of this site? Confirm its status | Allentown | United States | Recruiting |
| Community Hospital of Anaconda Coordinator of this site? Confirm its status | Anaconda | United States | Recruiting |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor Coordinator of this site? Confirm its status | Ann Arbor | United States | Recruiting |
| Saint Alphonsus Cancer Care Center-Baker City Coordinator of this site? Confirm its status | Baker City | United States | Recruiting |
| Indu and Raj Soin Medical Center Coordinator of this site? Confirm its status | Beavercreek | United States | Recruiting |
| Nebraska Medicine-Bellevue Coordinator of this site? Confirm its status | Bellevue | United States | Recruiting |
| Lehigh Valley Hospital - Muhlenberg Coordinator of this site? Confirm its status | Bethlehem | United States | Recruiting |
| Billings Clinic Cancer Center Coordinator of this site? Confirm its status | Billings | United States | Recruiting |
| Illinois CancerCare-Bloomington Coordinator of this site? Confirm its status | Bloomington | United States | Recruiting |
| Saint Elizabeth Boardman Hospital Coordinator of this site? Confirm its status | Boardman | United States | Recruiting |
| Saint Alphonsus Cancer Care Center-Boise Coordinator of this site? Confirm its status | Boise | United States | Recruiting |
| Bozeman Health Deaconess Hospital Coordinator of this site? Confirm its status | Bozeman | United States | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton Coordinator of this site? Confirm its status | Brighton | United States | Recruiting |
| Trinity Health Medical Center - Brighton Coordinator of this site? Confirm its status | Brighton | United States | Recruiting |
| Minnesota Oncology - Burnsville Coordinator of this site? Confirm its status | Burnsville | United States | Recruiting |
| Saint Alphonsus Cancer Care Center-Caldwell Coordinator of this site? Confirm its status | Caldwell | United States | Recruiting |
| Cambridge Medical Center Coordinator of this site? Confirm its status | Cambridge | United States | Recruiting |
| Illinois CancerCare-Canton Coordinator of this site? Confirm its status | Canton | United States | Recruiting |
| Trinity Health Medical Center - Canton Coordinator of this site? Confirm its status | Canton | United States | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Canton Coordinator of this site? Confirm its status | Canton | United States | Recruiting |
| Southeast Cancer Center Coordinator of this site? Confirm its status | Cape Girardeau | United States | Recruiting |
| Saint Francis Medical Center Coordinator of this site? Confirm its status | Cape Girardeau | United States | Recruiting |
| Memorial Hospital of Carbondale Coordinator of this site? Confirm its status | Carbondale | United States | Recruiting |
| Caro Cancer Center Coordinator of this site? Confirm its status | Caro | United States | Recruiting |
| SIH Cancer Institute Coordinator of this site? Confirm its status | Carterville | United States | Recruiting |
| Illinois CancerCare-Carthage Coordinator of this site? Confirm its status | Carthage | United States | Recruiting |
| Oncology Associates at Mercy Medical Center Coordinator of this site? Confirm its status | Cedar Rapids | United States | Recruiting |
| Mercy Hospital Coordinator of this site? Confirm its status | Cedar Rapids | United States | Recruiting |
| Dayton Physicians LLC-Miami Valley South Coordinator of this site? Confirm its status | Centerville | United States | Recruiting |
| Centralia Oncology Clinic Coordinator of this site? Confirm its status | Centralia | United States | Recruiting |
| Christiana Care Health System-Concord Health Center Coordinator of this site? Confirm its status | Chadds Ford | United States | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Coordinator of this site? Confirm its status | Chelsea | United States | Recruiting |
| Chelsea Hospital Coordinator of this site? Confirm its status | Chelsea | United States | Recruiting |
| University of Illinois Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| Oncology Hematology Care Inc-Kenwood Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| Newland Medical Associates-Clarkston Coordinator of this site? Confirm its status | Clarkston | United States | Recruiting |
| Hematology Oncology Consultants-Clarkston Coordinator of this site? Confirm its status | Clarkston | United States | Recruiting |
| Billings Clinic-Cody Coordinator of this site? Confirm its status | Cody | United States | Recruiting |
| Kootenai Health - Coeur d'Alene Coordinator of this site? Confirm its status | Coeur d'Alene | United States | Recruiting |
| MD Anderson in The Woodlands Coordinator of this site? Confirm its status | Conroe | United States | Recruiting |
| Mercy Hospital Coordinator of this site? Confirm its status | Coon Rapids | United States | Recruiting |
| Dayton Physician LLC - Englewood Coordinator of this site? Confirm its status | Dayton | United States | Recruiting |
| Decatur Memorial Hospital Coordinator of this site? Confirm its status | Decatur | United States | Recruiting |
| Cancer Care Specialists of Illinois - Decatur Coordinator of this site? Confirm its status | Decatur | United States | Recruiting |
| Northwestern Medicine Cancer Center Kishwaukee Coordinator of this site? Confirm its status | DeKalb | United States | Recruiting |
| Henry Ford Health Saint John Hospital Coordinator of this site? Confirm its status | Detroit | United States | Recruiting |
| Illinois CancerCare-Dixon Coordinator of this site? Confirm its status | Dixon | United States | Recruiting |
| Great Lakes Cancer Management Specialists-Doctors Park Coordinator of this site? Confirm its status | East China Township | United States | Recruiting |
| Pocono Medical Center Coordinator of this site? Confirm its status | East Stroudsburg | United States | Recruiting |
| Fairview Southdale Hospital Coordinator of this site? Confirm its status | Edina | United States | Recruiting |
| Crossroads Cancer Center Coordinator of this site? Confirm its status | Effingham | United States | Recruiting |
| Christiana Care - Union Hospital Coordinator of this site? Confirm its status | Elkton | United States | Recruiting |
| Illinois CancerCare-Eureka Coordinator of this site? Confirm its status | Eureka | United States | Recruiting |
| Parkland Health Center - Farmington Coordinator of this site? Confirm its status | Farmington | United States | Recruiting |
| Highlands Oncology Group - Fayetteville Coordinator of this site? Confirm its status | Fayetteville | United States | Recruiting |
| Armes Family Cancer Center Coordinator of this site? Confirm its status | Findlay | United States | Recruiting |
| Orion Cancer Care Coordinator of this site? Confirm its status | Findlay | United States | Recruiting |
| Blanchard Valley Hospital Coordinator of this site? Confirm its status | Findlay | United States | Recruiting |
| Hurley Medical Center Coordinator of this site? Confirm its status | Flint | United States | Recruiting |
| Genesys Hurley Cancer Institute Coordinator of this site? Confirm its status | Flint | United States | Recruiting |
| Genesee Cancer and Blood Disease Treatment Center Coordinator of this site? Confirm its status | Flint | United States | Recruiting |
| Genesee Hematology Oncology PC Coordinator of this site? Confirm its status | Flint | United States | Recruiting |
| Holy Cross Hospital Coordinator of this site? Confirm its status | Fort Lauderdale | United States | Recruiting |
| Dayton Physicians LLC-Atrium Coordinator of this site? Confirm its status | Franklin | United States | Recruiting |
| Western Illinois Cancer Treatment Center Coordinator of this site? Confirm its status | Galesburg | United States | Recruiting |
| Illinois CancerCare-Galesburg Coordinator of this site? Confirm its status | Galesburg | United States | Recruiting |
| Northwestern Medicine Cancer Center Delnor Coordinator of this site? Confirm its status | Geneva | United States | Recruiting |
| The West Clinic - Wolf River Coordinator of this site? Confirm its status | Germantown | United States | Recruiting |
| Northwestern Medicine Glenview Outpatient Center Coordinator of this site? Confirm its status | Glenview | United States | Recruiting |
| Northwestern Medicine Grayslake Outpatient Center Coordinator of this site? Confirm its status | Grayslake | United States | Recruiting |
| Great Falls Clinic Coordinator of this site? Confirm its status | Great Falls | United States | Recruiting |
| Benefis Sletten Cancer Institute Coordinator of this site? Confirm its status | Great Falls | United States | Recruiting |
| Wayne Hospital Coordinator of this site? Confirm its status | Greenville | United States | Recruiting |
| Dayton Physicians LLC-Wayne Coordinator of this site? Confirm its status | Greenville | United States | Recruiting |
| Great Lakes Cancer Management Specialists-Van Elslander Cancer Center Coordinator of this site? Confirm its status | Grosse Pointe Woods | United States | Recruiting |
| Henry Ford Saint John Hospital - Academic Coordinator of this site? Confirm its status | Grosse Pointe Woods | United States | Recruiting |
| Henry Ford Saint John Hospital - Breast Coordinator of this site? Confirm its status | Grosse Pointe Woods | United States | Recruiting |
| Lehigh Valley Hospital-Hazleton Coordinator of this site? Confirm its status | Hazleton | United States | Recruiting |
| MD Anderson West Houston Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| Lyndon Baines Johnson General Hospital Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| M D Anderson Cancer Center Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| University of Mississippi Medical Center Coordinator of this site? Confirm its status | Jackson | United States | Recruiting |
| Kalispell Regional Medical Center Coordinator of this site? Confirm its status | Kalispell | United States | Recruiting |
| Greater Dayton Cancer Center Coordinator of this site? Confirm its status | Kettering | United States | Recruiting |
| Kettering Medical Center Coordinator of this site? Confirm its status | Kettering | United States | Recruiting |
| Illinois CancerCare-Kewanee Clinic Coordinator of this site? Confirm its status | Kewanee | United States | Recruiting |
| Northwestern Medicine Lake Forest Hospital Coordinator of this site? Confirm its status | Lake Forest | United States | Recruiting |
| University of Michigan Health - Sparrow Lansing Coordinator of this site? Confirm its status | Lansing | United States | Recruiting |
| MD Anderson League City Coordinator of this site? Confirm its status | League City | United States | Recruiting |
| Beebe Medical Center Coordinator of this site? Confirm its status | Lewes | United States | Recruiting |
| Trinity Health Saint Mary Mercy Livonia Hospital Coordinator of this site? Confirm its status | Livonia | United States | Recruiting |
| Tibor Rubin VA Medical Center Coordinator of this site? Confirm its status | Long Beach | United States | Recruiting |
| Henry Ford Warren Hospital - Breast Macomb Coordinator of this site? Confirm its status | Macomb | United States | Recruiting |
| Great Lakes Cancer Management Specialists-Macomb Medical Campus Coordinator of this site? Confirm its status | Macomb | United States | Recruiting |
| Illinois CancerCare-Macomb Coordinator of this site? Confirm its status | Macomb | United States | Recruiting |
| Fairview Clinics and Surgery Center Maple Grove Coordinator of this site? Confirm its status | Maple Grove | United States | Recruiting |
| Saint John's Hospital - Healtheast Coordinator of this site? Confirm its status | Maplewood | United States | Recruiting |
| Minnesota Oncology Hematology PA-Maplewood Coordinator of this site? Confirm its status | Maplewood | United States | Recruiting |
| Saint Mary's Oncology/Hematology Associates of Marlette Coordinator of this site? Confirm its status | Marlette | United States | Recruiting |
| Idaho Urologic Institute-Meridian Coordinator of this site? Confirm its status | Meridian | United States | Recruiting |
| Beebe South Coastal Health Campus Coordinator of this site? Confirm its status | Millville | United States | Recruiting |
| Health Partners Inc Coordinator of this site? Confirm its status | Minneapolis | United States | Recruiting |
| Hennepin County Medical Center Coordinator of this site? Confirm its status | Minneapolis | United States | Recruiting |
| Abbott-Northwestern Hospital Coordinator of this site? Confirm its status | Minneapolis | United States | Recruiting |
| Community Medical Center Coordinator of this site? Confirm its status | Missoula | United States | Recruiting |
| Monticello Cancer Center Coordinator of this site? Confirm its status | Monticello | United States | Recruiting |
| Saint Alphonsus Cancer Care Center-Nampa Coordinator of this site? Confirm its status | Nampa | United States | Recruiting |
| Christiana Care Health System-Christiana Hospital Coordinator of this site? Confirm its status | Newark | United States | Recruiting |
| Medical Oncology Hematology Consultants PA Coordinator of this site? Confirm its status | Newark | United States | Recruiting |
| Helen F Graham Cancer Center Coordinator of this site? Confirm its status | Newark | United States | Recruiting |
| Cancer Center of Western Wisconsin Coordinator of this site? Confirm its status | New Richmond | United States | Recruiting |
| New Ulm Medical Center Coordinator of this site? Confirm its status | New Ulm | United States | Recruiting |
| HSHS Saint Elizabeth's Hospital Coordinator of this site? Confirm its status | O'Fallon | United States | Recruiting |
| Cancer Care Center of O'Fallon Coordinator of this site? Confirm its status | O'Fallon | United States | Recruiting |
| University of Oklahoma Health Sciences Center Coordinator of this site? Confirm its status | Oklahoma City | United States | Recruiting |
| Nebraska Medicine-Village Pointe Coordinator of this site? Confirm its status | Omaha | United States | Recruiting |
| University of Nebraska Medical Center Coordinator of this site? Confirm its status | Omaha | United States | Recruiting |
| Saint Alphonsus Cancer Care Center-Ontario Coordinator of this site? Confirm its status | Ontario | United States | Recruiting |
| Northwestern Medicine Orland Park Coordinator of this site? Confirm its status | Orland Park | United States | Recruiting |
| Illinois CancerCare-Ottawa Clinic Coordinator of this site? Confirm its status | Ottawa | United States | Recruiting |
| Illinois CancerCare-Pekin Coordinator of this site? Confirm its status | Pekin | United States | Recruiting |
| Methodist Medical Center of Illinois Coordinator of this site? Confirm its status | Peoria | United States | Recruiting |
| Illinois CancerCare-Peoria Coordinator of this site? Confirm its status | Peoria | United States | Recruiting |
| Valley Radiation Oncology Coordinator of this site? Confirm its status | Peru | United States | Recruiting |
| Illinois CancerCare-Peru Coordinator of this site? Confirm its status | Peru | United States | Recruiting |
| Trinity Health Saint Joseph Mercy Oakland Hospital Coordinator of this site? Confirm its status | Pontiac | United States | Recruiting |
| Newland Medical Associates-Pontiac Coordinator of this site? Confirm its status | Pontiac | United States | Recruiting |
| Michigan Healthcare Professionals Pontiac Coordinator of this site? Confirm its status | Pontiac | United States | Recruiting |
| Hope Cancer Center Coordinator of this site? Confirm its status | Pontiac | United States | Recruiting |
| Kootenai Clinic Cancer Services - Post Falls Coordinator of this site? Confirm its status | Post Falls | United States | Recruiting |
| Illinois CancerCare-Princeton Coordinator of this site? Confirm its status | Princeton | United States | Recruiting |
| Fairview Northland Medical Center Coordinator of this site? Confirm its status | Princeton | United States | Recruiting |
| Beebe Health Campus Coordinator of this site? Confirm its status | Rehoboth Beach | United States | Recruiting |
| Reid Health Coordinator of this site? Confirm its status | Richmond | United States | Recruiting |
| VCU Massey Cancer Center at Stony Point Coordinator of this site? Confirm its status | Richmond | United States | Recruiting |
| Virginia Commonwealth University/Massey Cancer Center Coordinator of this site? Confirm its status | Richmond | United States | Recruiting |
| North Memorial Medical Health Center Coordinator of this site? Confirm its status | Robbinsdale | United States | Recruiting |
| Highlands Oncology Group - Rogers Coordinator of this site? Confirm its status | Rogers | United States | Recruiting |
| MyMichigan Medical Center Saginaw Coordinator of this site? Confirm its status | Saginaw | United States | Recruiting |
| Oncology Hematology Associates of Saginaw Valley PC Coordinator of this site? Confirm its status | Saginaw | United States | Recruiting |
| Sainte Genevieve County Memorial Hospital Coordinator of this site? Confirm its status | Sainte Genevieve | United States | Recruiting |
| Park Nicollet Clinic - Saint Louis Park Coordinator of this site? Confirm its status | Saint Louis Park | United States | Recruiting |
| United Hospital Coordinator of this site? Confirm its status | Saint Paul | United States | Recruiting |
| Regions Hospital Coordinator of this site? Confirm its status | Saint Paul | United States | Recruiting |
| Kootenai Clinic Cancer Services - Sandpoint Coordinator of this site? Confirm its status | Sandpoint | United States | Recruiting |
| Saint Francis Regional Medical Center Coordinator of this site? Confirm its status | Shakopee | United States | Recruiting |
| Welch Cancer Center Coordinator of this site? Confirm its status | Sheridan | United States | Recruiting |
| Highlands Oncology Group Coordinator of this site? Confirm its status | Springdale | United States | Recruiting |
| Southern Illinois University School of Medicine Coordinator of this site? Confirm its status | Springfield | United States | Recruiting |
| Springfield Clinic Coordinator of this site? Confirm its status | Springfield | United States | Recruiting |
| Memorial Medical Center Coordinator of this site? Confirm its status | Springfield | United States | Recruiting |
| Lakeview Hospital Coordinator of this site? Confirm its status | Stillwater | United States | Recruiting |
| Missouri Baptist Medical Center Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| MD Anderson in Sugar Land Coordinator of this site? Confirm its status | Sugar Land | United States | Recruiting |
| Missouri Baptist Sullivan Hospital Coordinator of this site? Confirm its status | Sullivan | United States | Recruiting |
| BJC Outpatient Center at Sunset Hills Coordinator of this site? Confirm its status | Sunset Hills | United States | Recruiting |
| MyMichigan Medical Center Tawas Coordinator of this site? Confirm its status | Tawas City | United States | Recruiting |
| Dayton Physicians LLC - Troy Coordinator of this site? Confirm its status | Troy | United States | Recruiting |
| Ridgeview Medical Center Coordinator of this site? Confirm its status | Waconia | United States | Recruiting |
| Saint Joseph Warren Hospital Coordinator of this site? Confirm its status | Warren | United States | Recruiting |
| Great Lakes Cancer Management Specialists-Macomb Professional Building Coordinator of this site? Confirm its status | Warren | United States | Recruiting |
| Henry Ford Madison Heights Hospital - Breast Coordinator of this site? Confirm its status | Warren | United States | Recruiting |
| Saint John Macomb-Oakland Hospital Coordinator of this site? Confirm its status | Warren | United States | Recruiting |
| Northwestern Medicine Cancer Center Warrenville Coordinator of this site? Confirm its status | Warrenville | United States | Recruiting |
| Illinois CancerCare - Washington Coordinator of this site? Confirm its status | Washington | United States | Recruiting |
| Saint Mary's Oncology/Hematology Associates of West Branch Coordinator of this site? Confirm its status | West Branch | United States | Recruiting |
| Rice Memorial Hospital Coordinator of this site? Confirm its status | Willmar | United States | Recruiting |
| Christiana Care Health System-Wilmington Hospital Coordinator of this site? Confirm its status | Wilmington | United States | Recruiting |
| Minnesota Oncology Hematology PA-Woodbury Coordinator of this site? Confirm its status | Woodbury | United States | Recruiting |
| Fairview Lakes Medical Center Coordinator of this site? Confirm its status | Wyoming | United States | Recruiting |
| Saint Elizabeth Youngstown Hospital Coordinator of this site? Confirm its status | Youngstown | United States | Recruiting |
| Huron Gastroenterology PC Coordinator of this site? Confirm its status | Ypsilanti | United States | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Coordinator of this site? Confirm its status | Ypsilanti | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.