NCT06470516Recruiting
The Hi-tACS on Cognitive Function in Patients With Schizophrenia
The Impact of High-frequency Transcranial Alternating Current Stimulation (Hi-tACS) on Cognitive Function in Patients With Schizophrenia
Source: ClinicalTrials.gov · Last updated 2 Mar 2026
Brief summary (registry, in English)
This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with schizophrenia.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 17 Jun 2024
- Start date
- 1 Apr 2024
- Primary completion date
- 31 Mar 2026
- Lead sponsor
- Sir Run Run Shaw Hospital
- Diseases
- Schizophrenia
- NCT number
- NCT06470516
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Apr 2024 to the primary completion date, 31 Mar 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Those who have received MECT or TMS treatment within 1 month before enrollment.
- Implants of metal or electronic devices (such as pacemakers, cochlear implants, deep brain stimulators, aneurysm clips, internal fixation devices after ventriculoperitoneal shunt surgery, etc.).
- Participation in any other clinical trials within 1 month prior to baseline.
Other illness
- Psychotic disorders caused by split affective disorder, bipolar disorder, intellectual disability, anxiety spectrum disorders, drugs, alcohol, and other psychoactive substances according to DSM-V diagnostic criteria.
- Those with severe or unstable organic diseases, with a history of brain tumors or epilepsy.
- Skin integrity at the electrode placement site is compromised. Allergy to electrode gel or adhesive.
- The investigator believes that there are inappropriate conditions for participating in this study.
Other
- Pregnant and lactating women.
Who the study is looking for
- Meets the diagnostic criteria for schizophrenia according to DSM-5.
- Age ≥ 18 years old.
- Right-handed.
- Willing to participate in this study and sign an informed consent form. If the participant is unable to read and sign the informed consent form due to lack of capacity, a legal guardian must act as a proxy during the informed consent process and sign the form.
- Clinically stable, receiving antipsychotic medication treatment with a stable dose for 4 weeks without any changes.
- Montreal Cognitive Assessment score ≥ 10 points.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sir Run Run Shaw Hospital Coordinator of this site? Confirm its status | Hanzhou | China | Recruiting |
| Quzhou Third Hospital Coordinator of this site? Confirm its status | Quzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.