NCT06471491Completed
Driving Pressure-guided Positive End-expiratory Pressure to Prevent Postoperative Atelectasis in Obese Children: a Prospective, Randomized Controlled Clinical Trial
Source: ClinicalTrials.gov · Last updated 23 Jul 2025
Brief summary (registry, in English)
At present, the use of lung protective ventilation strategies in children is mainly based on adult and intensive care unit data. Although obese children may benefit more from lung protective ventilation, there are few studies on the use of lung protective ventilation strategies in obese children during surgery. Therefore, the investigators hypothesized that intraoperative use of LPV strategies in obese pediatric surgery patients can reduce atelectasis and improve the incidence of postoperative pulmonary complications.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 31 May 2024
- Start date
- 11 Sept 2024
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Henan Provincial People's Hospital
- Diseases
- Obesity
- NCT number
- NCT06471491
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 11 Sept 2024 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- PEEP contraindications: (a) bronchopleural fistula; (b) hypovolemic shock; (c) right ventricular failure;
- Pulmonary dysfunction, congenital heart disease children;
- Children with upper respiratory tract infection within 2 weeks.
Other
- American Society of Anesthesiologists (ASA) grade greater than II;
- Refusal to participate in the study and/or use personal data, preoperative intubation or ventilation of children;
Who the study is looking for
- Age 3-18 years old;
- According to the People's Republic of China health industry standard "Overweight and Obesity Screening threshold for school-age children and adolescents WS\_T586-2018" defined as obesity;
- American Society of Anesthesiologists (ASA) grades I - II;
- Children with healthy lungs and hearts;
- Patients with general anesthesia under tracheal intubation;
- Clear mind and able to cooperate with the anesthesiologist to receive treatment;
- Patients who plan to have elective surgery under general anesthesia and the estimated operation duration is ≥2 hours.
Age in the registry: 3 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Henan Provincial People's Hospital Coordinator of this site? Confirm its status | Zhengzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.