NCT06474117Completed
Muscle-tendon Interaction in the Spastic Sural Triceps During Gait
Source: ClinicalTrials.gov · Last updated 4 Mar 2026
Brief summary (registry, in English)
This project aims to study the mechanical behavior of the muscle-tendon unit (MTU) of the gastrocnemius medialis (GM) and the Achilles tendon (AT) in post-stroke and spinal cord injured (SCI) patients compared to a healthy population, focusing on the variations in muscle and tendon length during the stance phase of the gait cycle. The primary objective is to assess the respective contributions of the GM and AT lengthening in the MTU during walking. Inclusion criteria include adult post-stroke and post-SCI patients with voluntary motor function and some walking capacity. Methods include ultrasound measurements and 3D gait analysis.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 64 (actual)
- First submitted
- 19 Jun 2024
- Start date
- 15 Nov 2024
- Primary completion date
- 17 Feb 2026
- Lead sponsor
- Nantes University Hospital
- Diseases
- Stroke
- NCT number
- NCT06474117
What you commit to
- Study type: Observational
- Participants enrolled: 64
- From 15 Nov 2024 to the primary completion date, 17 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Post-Stroke and Post-Spinal Cord Injury Population:
- History of calf surgery, surgery to reduce triceps surae spasticity, or intramuscular injection (e.g., botulinum toxin) in the plantar flexors within the last 6 months
- Patient with a progressive condition contraindicating physical exertion (e.g., syrinx, cardiovascular instability)
- History of calf surgery
- History of muscle injury, fracture, or sprain of the lower limb within the last 3 months
- History of neurological disorders
Other
- Minor patient
- Peripheral pathology of the considered lower limb
- Healthy Population:
Who the study is looking for
- Post-Stroke Population:
- Adult male or female
- Patient who had a stroke more than 7 days ago
- Patient hospitalized (in conventional hospitalization or day hospital) in the university neurological rehabilitation department of CHU de Nantes
- Patient with voluntary motor function graded between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
- Patient classified between 3 and 8 on the New Functional Ambulation Classification
- Post-Spinal Cord Injury Population:
- Adult male or female
- Patient with an incomplete spinal cord injury classified as ASIA AIS C or D from level C2 to L5
- Patient hospitalized (in conventional hospitalization or day hospital) in the neurological rehabilitation department of CHU de Nantes
- Patient with voluntary motor function graded between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
- Patient classified between 3 and 8 on the New Functional Ambulation Classification
- Healthy Population:
- Adult male or female without any neurological disorders
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Nantes Coordinator of this site? Confirm its status | Nantes | France | Unknown status |
Related publications
- Impaired gastrocnemius medialis muscle-tendon decoupling reduces gait efficiency in spastic paresis syndrome.Ann Phys Rehabil Med · 2026 · PMID 42551247
This page is information, not medical advice. Discuss any trial with your doctor.