NCT06474624Completed
Evaluation of the Effects of Training at Different Intensities in Coronary Artery Patients
Evaluation of the Effects of High-Intensity-Intermittent Training and Moderate-Intensity Continuous Training on Heart Rate Recovery, Functional Capacity, Fatigue and Quality of Life in Coronary Artery Patients
Source: ClinicalTrials.gov · Last updated 27 Jun 2024
Brief summary (registry, in English)
Coronary heart disease (CHD) remains the leading cause of morbidity and mortality in developed countries, accounting for approximately one-third of all deaths in individuals over 35 years of age. Despite research to date, the basis of the disease is still poorly understood, with chronic dysfunction of the autonomic nervous system being proposed as such a basis, as well as pathophysiological and pathogenic approaches. Hypertension has been implicated in the development of cardiovascular risk factors such as diabetes and dyslipidaemia and is directly linked to mortality caused by coronary artery disease. Moderate Intensity Continuous Training (MICT) has been recognised as the gold standard for many years. However, for some time, different researchers have adopted the high-intensity interval training model (HIIT) as the most effective method in terms of objective adaptations of most cardiac rehabilitation programmes in patients with coronary artery disease (CAD) and congestive heart failure. High-intensity interval training (HIIT) consists of cycles between warm-up and cool-down periods, high-intensity exercise intensity followed by an active recovery period. The duration and intensity of these cycles vary between studies and there is no consensus on which is the optimal cycle. In general, the high-intensity exercise phase is applied at 80-100% of VO2 max and the active recovery phase is used between 50-70% of VO2 max. In Moderate Intensity Continuous Training the submaximal exercise intensity determined in accordance with the patient's functional capacity between the warm-up and cool-down periods is applied for a fixed period. The Moderate Intensity Continuous Training is planned to consist of 20-30 minute sessions between 50-70% of maximum oxygen consumption (VO2max).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 78 (actual)
- First submitted
- 20 Jun 2024
- Start date
- 26 May 2023
- Primary completion date
- 1 May 2024
- Lead sponsor
- Kutahya Health Sciences University
- Diseases
- Coronary artery disease
- NCT number
- NCT06474624
What you commit to
- Study type: Interventional
- Participants enrolled: 78
- From 26 May 2023 to the primary completion date, 1 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Being in Class III-IV according to the New York Heart Classification,
- Ventricular arrhythmia,
- Significant valvular heart disease,
- Failure to comply with the rules of exercise testing and training,
- Metabolic, haematological or other inflammatory diseases
- Known psychiatric illness
- Active malignancy and/or those diagnosed with malignancy within the last 5 years
- History of major orthopaedic surgery within the last 6 months.
Other
- Symptoms of ischaemia,
- Presence of significant left ventricular outflow obstruction,
- Significant orthopaedic or neurological comorbidity preventing full participation.
- Less than 80% participation in the treatment programme
- Those who have used tobacco products in the last 5 years
- BMI \>35
Who the study is looking for
- Being between the ages of 30 and 65,
- Being with stable New York Heart Association functional class I or II coronary artery disease with angina pectoris or myocardial infarction,
- Having a left ventricular ejection fraction of 40% or above,
- Being clinically stable for more than 2 weeks in terms of symptoms and medical treatment.
Age in the registry: 30 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kutahya University of Health Sciences Evliya Çelebi Physical Medicine and Rehabilitation Clinic, Cardiopulmonary Rehabilitation Unit Coordinator of this site? Confirm its status | Kütahya | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.