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NCT06475118Recruiting

Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma

Source: ClinicalTrials.gov · Last updated 26 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

It is known that some substances present in the blood, called 'myokines,' influence muscle loss. Some may accelerate this loss, while others may prevent it. Inflammatory substances in the blood can also contribute to muscle loss. Sarcopenia is assessed by an imaging technique called 'Skeletal Muscle Mass Index (SMI)' to measure muscle mass. This analysis can be done from radiological examinations. Sarcopenia has a serious impact on patients with hepatocellular carcinoma. It increases the risk of death, cancer recurrence, and decreases the response to treatments. Therefore, the investigators want to determine if blood tests for myokines obtained by simple blood draw can improve the assessment of sarcopenia in this specific setting.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
139 (estimated)
First submitted
20 Jun 2024
Start date
22 Nov 2024
Primary completion date
22 Nov 2025
Lead sponsor
CHU de Reims
NCT number
NCT06475118

What you commit to

  • Study type: Interventional
  • Planned participants: 139
  • From 22 Nov 2024 to the primary completion date, 22 Nov 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

  • New diagnosis of HCC made by radiology and/or histopathology according to EASL criteria, regardless of the degree of hepatic fibrosis (METAVIR F0-F4)
  • Availability of a pre-therapeutic three-phase contrast-enhanced abdominal-pelvic CT scan.
    • Non-inclusion criteria:
  • Presence of an active cancer other than HCC
  • Uncontrolled HIV infection.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Damien JOLLY
Coordinator of this site? Confirm its status
ReimsFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.