NCT06475118Recruiting
Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma
Source: ClinicalTrials.gov · Last updated 26 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
It is known that some substances present in the blood, called 'myokines,' influence muscle loss. Some may accelerate this loss, while others may prevent it. Inflammatory substances in the blood can also contribute to muscle loss. Sarcopenia is assessed by an imaging technique called 'Skeletal Muscle Mass Index (SMI)' to measure muscle mass. This analysis can be done from radiological examinations. Sarcopenia has a serious impact on patients with hepatocellular carcinoma. It increases the risk of death, cancer recurrence, and decreases the response to treatments. Therefore, the investigators want to determine if blood tests for myokines obtained by simple blood draw can improve the assessment of sarcopenia in this specific setting.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 139 (estimated)
- First submitted
- 20 Jun 2024
- Start date
- 22 Nov 2024
- Primary completion date
- 22 Nov 2025
- Lead sponsor
- CHU de Reims
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT06475118
What you commit to
- Study type: Interventional
- Planned participants: 139
- From 22 Nov 2024 to the primary completion date, 22 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- New diagnosis of HCC made by radiology and/or histopathology according to EASL criteria, regardless of the degree of hepatic fibrosis (METAVIR F0-F4)
- Availability of a pre-therapeutic three-phase contrast-enhanced abdominal-pelvic CT scan.
- Non-inclusion criteria:
- Presence of an active cancer other than HCC
- Uncontrolled HIV infection.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Damien JOLLY Coordinator of this site? Confirm its status | Reims | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.