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NCT06475183Completed

Probiotic Chocolate Study in Multiple Sclerosis

Effects of Probiotics on Inflammatory Biomarkers in Persons With Multiple Sclerosis (MS) and in Family Members of Persons With MS

Source: ClinicalTrials.gov · Last updated 30 Mar 2025

Brief summary (registry, in English)

The goal of this study is to assess the effects of probiotics on persons with multiple sclerosis (MS), persons at higher genetic risk for MS (first degree family members of persons with MS), and healthy controls. Participants will be asked to consume probiotic containing chocolates (Bouchard Belgian Dark Chocolate Probiotic Napolitains containing 10 billion CFUs of bifidobacterium longum per day) for 6 weeks. Participants will undergo blood draws before and after the 6 weeks of probiotic containing chocolate and microbial metabolites and immune markers will be compared before and after the probiotics, as well as between groups.

Status (registry)
Completed
Study type
Interventional
Enrollment
92 (actual)
First submitted
20 Jun 2024
Start date
1 Jun 2024
Primary completion date
9 Dec 2024
Lead sponsor
Columbia University
NCT number
NCT06475183

What you commit to

  • Study type: Interventional
  • Participants enrolled: 92
  • From 1 Jun 2024 to the primary completion date, 9 Dec 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • diabetes
  • tree nut allergy

Other

  • pregnancy

Who the study is looking for

  • Multiple Sclerosis (MS) subjects, first-degree relatives of MS subjects, or healthy controls
  • Age 18-45

Age in the registry: 18 years to 45 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Columbia University Irving Medical Center
Coordinator of this site? Confirm its status
New YorkUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.