NCT06479915Completed
Estimate the Relationship Between Oral Microbiota and Stroke
Access the Influence of Oral Microbiota in the Onset and Evolution of Stroke, With Focus on Cerebral Microbleeds
Source: ClinicalTrials.gov · Last updated 7 Aug 2025
Brief summary (registry, in English)
Oral bacteria constitute the second largest population of the human microbiome. Recent studies have identified their role in the development of systemic diseases, such as cardiovascular and cerebrovascular diseases. Streptococcus Mutans (SM) is considered the primary pathogen responsible for dental caries. Furthermore, in cases of oral inflammatory diseases, SM has been found to invade the bloodstream and disseminate, leading to systemic diseases. Against this backdrop, this study aims to investigate disparities in oral flora between stroke patients and healthy individuals by collecting saliva samples from both groups.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 170 (actual)
- First submitted
- 19 Jun 2024
- Start date
- 1 Apr 2024
- Primary completion date
- 28 Feb 2025
- Lead sponsor
- Fujian Medical University
- Diseases
- Stroke
- NCT number
- NCT06479915
What you commit to
- Study type: Observational
- Participants enrolled: 170
- From 1 Apr 2024 to the primary completion date, 28 Feb 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have received antibiotic quality within the last three months
Who the study is looking for
- 1\. Microbleeding/damage or rupture of small blood vessels in the brain has been diagnosed within the past 365 days 2. Have done nuclear magnetic examination and can provide nuclear magnetic results
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| School and Hospital of stomatology,Fujian Medical University,Fuzhou,Fujian Province,350002,China Coordinator of this site? Confirm its status | Fuzhou | China | Unknown status |
| The First Affiliated Hospital of Fujian Medical University Coordinator of this site? Confirm its status | Fuzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.