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NCT06480734Active, not recruiting

Pneumonitis in Older Lung Cancer Patients After Radiotherapy

Pneumonitis in Older Lung Cancer Patients After Radiotherapy: a Scoring System for Identification of Pneumonitis in Elderly Patients Irradiated for Lung Cancer

Source: ClinicalTrials.gov · Last updated 16 Jan 2025

Brief summary (registry, in English)

The main goal of this trial is to establish the performance characteristics and to develop a decision-algorithm of a new symptom-based scoring system with respect to the identification of elderly lung cancer patients developing pneumonitis after radiotherapy. To assess the performance characteristics of the symptom-based scoring system for detection of radiation pneumonitis the receiver operating characteristic (ROC) curve is used to show the connection between sensitivity and specificity for every possible cut-off for the symptom-based scoring system and to select the optimal scoring point for detection of radiation pneumonitis. The area under the ROC curve (AUC) is calculated to prove the diagnostic ability of the scoring system. Secondary aims include patient satisfaction with the symptom-based scoring system (symptom-questionnaire, paper version).

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
62 (estimated)
First submitted
24 Jun 2024
Start date
6 Nov 2024
Primary completion date
30 Jun 2026
Lead sponsor
University Hospital Schleswig-Holstein
Diseases
Lung cancer
NCT number
NCT06480734

What you commit to

  • Study type: Interventional
  • Planned participants: 62
  • From 6 Nov 2024 to the primary completion date, 30 Jun 2026
  • 5 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Expected Non-Compliance
  • Baseline score of \>4 points

Who the study is looking for

  • Histologically proven lung cancer
  • Indication for radiotherapy or chemoradiation
  • Mean radiation dose to ipsilateral lung \>13 Gy
  • Age ≥65 years
  • Written informed consent
  • Capacity of the patient to contract

Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (5)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Malteser Hospital St. Franziskus
Coordinator of this site? Confirm its status
FlensburgGermanyUnknown status
Medical Practice for Radiotherapy and Radiation Oncology
Coordinator of this site? Confirm its status
HanoverGermanyUnknown status
Department of Radiation Oncology, University of Lübeck and University Medical Center Schleswig-Holstein
Coordinator of this site? Confirm its status
LübeckGermanyUnknown status
Medical School Hamburg, Schwerin Campus
Coordinator of this site? Confirm its status
SchwerinGermanyUnknown status
Vejle Hospital, University Hospital of Southern Denmark
Coordinator of this site? Confirm its status
VejleDenmarkUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.