NCT06480734Active, not recruiting
Pneumonitis in Older Lung Cancer Patients After Radiotherapy
Pneumonitis in Older Lung Cancer Patients After Radiotherapy: a Scoring System for Identification of Pneumonitis in Elderly Patients Irradiated for Lung Cancer
Source: ClinicalTrials.gov · Last updated 16 Jan 2025
Brief summary (registry, in English)
The main goal of this trial is to establish the performance characteristics and to develop a decision-algorithm of a new symptom-based scoring system with respect to the identification of elderly lung cancer patients developing pneumonitis after radiotherapy. To assess the performance characteristics of the symptom-based scoring system for detection of radiation pneumonitis the receiver operating characteristic (ROC) curve is used to show the connection between sensitivity and specificity for every possible cut-off for the symptom-based scoring system and to select the optimal scoring point for detection of radiation pneumonitis. The area under the ROC curve (AUC) is calculated to prove the diagnostic ability of the scoring system. Secondary aims include patient satisfaction with the symptom-based scoring system (symptom-questionnaire, paper version).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 62 (estimated)
- First submitted
- 24 Jun 2024
- Start date
- 6 Nov 2024
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- University Hospital Schleswig-Holstein
- Diseases
- Lung cancer
- NCT number
- NCT06480734
What you commit to
- Study type: Interventional
- Planned participants: 62
- From 6 Nov 2024 to the primary completion date, 30 Jun 2026
- 5 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Expected Non-Compliance
- Baseline score of \>4 points
Who the study is looking for
- Histologically proven lung cancer
- Indication for radiotherapy or chemoradiation
- Mean radiation dose to ipsilateral lung \>13 Gy
- Age ≥65 years
- Written informed consent
- Capacity of the patient to contract
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Malteser Hospital St. Franziskus Coordinator of this site? Confirm its status | Flensburg | Germany | Unknown status |
| Medical Practice for Radiotherapy and Radiation Oncology Coordinator of this site? Confirm its status | Hanover | Germany | Unknown status |
| Department of Radiation Oncology, University of Lübeck and University Medical Center Schleswig-Holstein Coordinator of this site? Confirm its status | Lübeck | Germany | Unknown status |
| Medical School Hamburg, Schwerin Campus Coordinator of this site? Confirm its status | Schwerin | Germany | Unknown status |
| Vejle Hospital, University Hospital of Southern Denmark Coordinator of this site? Confirm its status | Vejle | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.