NCT06482814Recruiting
Sleep Restriction and Parental History of Hypertension
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 44 (estimated)
- First submitted
- 26 Jun 2024
- Start date
- 20 Feb 2025
- Primary completion date
- Apr 2029
- Lead sponsor
- Mayo Clinic
- Diseases
- High blood pressure
- NCT number
- NCT06482814
What you commit to
- Study type: Interventional
- Planned participants: 44
- From 20 Feb 2025 to the primary completion date, Apr 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of tobacco, vaping, marijuana products or other drugs
- Regular use of prescription medications other than contraceptives
Other illness
- Unable to determine history of HTN in participant's biological parents or subject being adopted
- History of significant medical or psychiatric disorders (as per the investigators' judgment)
- Restless leg syndrome (as per the Cambridge-Hopkins questionnaire)
Lab values
- Fasting glucose ≥126 mg/dl
- Exclusionary for blood draws: hemoglobin \<11.6 g/dL in women / \<13.2 g/dL in men; participants with measured hemoglobin levels below these thresholds will be allowed to continue participate in study tests and procedures not involving blood draws.
Age
- Age \<18 or \>35 years
Other
- Body mass index \<18.5 or ≥30 kg/m2
- Pregnant or lactating
- Excessive caffeine consumption (\>400 mg/day)
- Excessive alcohol consumption (\>7 drinks/week for women, \>14 drinks/week for men)
- Office SBP/DBP ≥130/80 mmHg
- Daytime ambulatory SBP/DBP ≥130/80 mmHg
- Glomerular filtration rate \<60 mL/min/BSA
- Use of melatonin supplements or any other over-the-counter sleep aid
- Moderate-to-severe sleep disordered breathing (apnea/hypopnea index, AHI ≥15) or mild sleep disordered breathing (AHI 5-15) with daytime sleepiness (Epworth Sleepiness Scale \>10)
- Moderate-to-severe insomnia (Insomnia Severity Index \>14)
- Excessive daytime sleepiness (Epworth Sleepiness Scale \>15)
- Extreme chronotype (Morningness-Eveningness Questionnaire \>69 or \<31)
- Night shift work
- Ongoing participation in other research studies (as per the investigators' judgment)
- Any other medical, geographic, or social factor making study participation impractical
- Not English-speaking and/or inability to provide informed consent
Who the study is looking for
- Healthy adults aged 18-35 years
- Absence of any significant medical or psychiatric disease (as per the investigators' judgment)
- Nonsmoker
- Nonpregnant
- History of normal sleep duration (reported average sleep duration between 7-9 hours/night and no habitual napping)
- Hypertension status information available for both biological parents
- Ability to understand study procedures and to comply with them for the entire length of the study
- Ability to understand English and provide informed consent
Age in the registry: 18 years to 35 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Rochester Coordinator of this site? Confirm its status | Rochester | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.