NCT06486636Recruiting
Pericardiotomy in Cardiac Surgery
Pericardiotomy in Cardiac Surgery Trial
Source: ClinicalTrials.gov · Last updated 21 Oct 2026
Brief summary (registry, in English)
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1400 (estimated)
- First submitted
- 13 Jun 2024
- Start date
- 21 Oct 2024
- Primary completion date
- 1 Sept 2027
- Lead sponsor
- Population Health Research Institute
- Diseases
- Atrial fibrillation
- NCT number
- NCT06486636
What you commit to
- Study type: Interventional
- Planned participants: 1400
- From 21 Oct 2024 to the primary completion date, 1 Sept 2027
- 19 sites in 5 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior cardiac surgery requiring opening of the pericardium
- Previous surgical instrumentation of the left pleural cavity
Other illness
- History of atrial fibrillation or flutter
- Cardiac surgery procedures not included in the inclusion criteria (planned ventricular assistance device, planned aortic arch, transplantation surgery)
- Patient undergoing minimally invasive cardiac surgery
Who the study is looking for
- Patients greater than or equal to 18 years of age
- Requiring surgical intervention on the proximal aorta, cardiac valves, and/or coronary arteries
- Able to provide informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (19)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of Innsbruck Coordinator of this site? Confirm its status | Innsbruck | Austria | Recruiting |
| Medical University Vienna Coordinator of this site? Confirm its status | Vienna | Austria | Recruiting |
| Nova Scotia Health Authority - Halifax Infirmary Coordinator of this site? Confirm its status | Halifax | Canada | Recruiting |
| Hamilton Health Sciences Coordinator of this site? Confirm its status | Hamilton | Canada | Active, not recruiting |
| Montreal Heart Institute Coordinator of this site? Confirm its status | Montreal | Canada | Active, not recruiting |
| Hôpital du Sacré-Cœur de Montréal Coordinator of this site? Confirm its status | Montreal | Canada | Recruiting |
| McGill University Health Centre, Royal Victoria Hospital Coordinator of this site? Confirm its status | Montreal | Canada | Recruiting |
| CHUM - Centre Hospitalier de l'Universite de Montreal Coordinator of this site? Confirm its status | Montreal | Canada | Active, not recruiting |
| St. Michael's Hospital Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
| Hospital Universitario del Vinalopo Coordinator of this site? Confirm its status | Alicante | Spain | Recruiting |
| Hospital Clínico San Carlos Coordinator of this site? Confirm its status | Madrid | Spain | Recruiting |
| Policlinico Foggia Coordinator of this site? Confirm its status | Foggia | Italy | Recruiting |
| University of Foggia, Policlinico Foggia Coordinator of this site? Confirm its status | Foggia | Italy | Recruiting |
| IRCSS Policlinico San Donato Coordinator of this site? Confirm its status | San Donato Milanese | Italy | Recruiting |
| Maria Pia Hospital Coordinator of this site? Confirm its status | Turin | Italy | Recruiting |
| San Bortolo Hospital Coordinator of this site? Confirm its status | Vicenza | Italy | Recruiting |
| Baylor College of Medicine Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| University of Louisville Coordinator of this site? Confirm its status | Louisville | United States | Recruiting |
| Weill Cornell Medicine Coordinator of this site? Confirm its status | New York | United States | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.