NCT06487975Completed
Bacillus Subtilis in Parkinson's Disease
Effects of Bacillus Subtilis on Blood and Gut Biomarkers in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 8 Apr 2026
Brief summary (registry, in English)
The aim of this study is to evaluate whether the administration of Bacillus Subtilis influences gut and blood biomarkers relevant to the proposed mechanism(s) of action, as well as being acceptable as a regular supplement for people with Parkinson's disease.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 26 (actual)
- First submitted
- 27 Mar 2024
- Start date
- 2 May 2023
- Primary completion date
- 5 Mar 2025
- Lead sponsor
- University of Edinburgh
- Diseases
- Parkinson disease
- NCT number
- NCT06487975
What you commit to
- Study type: Interventional
- Participants enrolled: 26
- From 2 May 2023 to the primary completion date, 5 Mar 2025
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous gastrointestinal surgery or chronic organic bowel disorder
- Regular use of antacids, proton pump inhibitors, laxatives or anti-diarrheal drugs
Other illness
- History of clinically significant motor fluctuations
- History of postural instability or falls
- Known or suspected allergy to probiotics
- Use of hypoglycaemic or diabetes drugs
Other
- Use of probiotic supplements and probiotic-fortified foods (such as probiotic drinks and yoghurts) within past 3 months
- Use of antibiotics within past 3 months
- Current smoker
- Participation in clinical trial of investigational medicinal product within past 3 months
- Co-morbidities or other factors that, in the opinion of the investigator, make the patient unlikely to comply with study protocol
Who the study is looking for
- Diagnosis of Parkinson's disease
- Able to provide written informed consent
- Over 50 years old
- Motor symptom duration over 12 months
- Stable dopaminergic medication regime for at least 3 months
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| NHS Lothian Coordinator of this site? Confirm its status | Edinburgh | United Kingdom | Unknown status |
| Norwegian Centre for Movement Disorders, Stavanger University Hospital Coordinator of this site? Confirm its status | Stavanger | Norway | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.