NCT06490003Recruiting
Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma
Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma by Biopsy Specimens.
Source: ClinicalTrials.gov · Last updated 13 Jul 2026
Brief summary (registry, in English)
Esophageal cancer remains a disease with a poor prognosis. Chemotherapy is an important part of its treatment, but there are cases in which chemotherapy is ineffective. The investigators aim to develop a model to predict the response to chemotherapy by DNA methylation of preoperative biopsy specimens to identify the chemotherapy ineffective group.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 21 Jun 2024
- Start date
- 1 Jun 2004
- Primary completion date
- 18 Jun 2028
- Lead sponsor
- City of Hope Medical Center
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT06490003
What you commit to
- Study type: Observational
- Planned participants: 150
- From 1 Jun 2004 to the primary completion date, 18 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who cannot assess at 2 months later after chemotherapy.
Other illness
- Patients with multiple cancers.
Other
- Patients for whom a preoperative biopsy sample cannot be obtained
Who the study is looking for
- Patients who had histologically confirmed esophageal squamous cell carcinoma.
- Patients who had undergone chemotherapy.
- Patients receiving initial chemotherapy
- Written informed consent following full study information is provided to the patient.
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yamanashi Universiy Coordinator of this site? Confirm its status | Chūō | Japan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.