NCT06491238Recruiting
Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
The overall purpose of this pilot study is to examine the feasibility, acceptability, and tolerability of light and moderate intensity exercise in adults with MGeffect of light vs. moderate intensity exercise on health outcomes. Participants will be enrolled into the NeuroWell exercise program, which is geared toward individuals with neurological disorders or injuries and led by Certified Exercise Physiologists (CEPs) at the HealthPartners Neuroscience Center. A total of 20 people with MG will be enrolled in this study and participate in a small group exercise program 3 times a week for 12 weeks. Participants will be randomized into two exercise groups: 1) Light intensity or 2) Moderate intensity. We hypothesize that light and moderate intensity exercise will be feasible, acceptable, and tolerable in adults with MG and that individuals in the light intensity exercise group will be able to achieve the same improvement in health outcomes as the moderate intensity group.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 21 Jun 2024
- Start date
- 16 Sept 2024
- Primary completion date
- Dec 2026
- Lead sponsor
- HealthPartners Institute
- Diseases
- Myasthenia gravis
- NCT number
- NCT06491238
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 16 Sept 2024 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Regular exercise participation within the month prior to study enrollment or any outside exercise participation during the study intervention period.
Other illness
- Significant cognitive impairment of any etiology that would impact study participation.
- History of heart failure, chronic lung disease, angina or any other condition that causes unreasonable shortness of breath on exertion.
- History of any serious neurological, psychiatric, or substance use disorders that would impact study participation.
- Any other medical conditions that could affect their ability to participate in exercise for the study duration (as determined by study investigators).
Other
- Non-English speaking
- Women who are currently pregnant or planning to become pregnant during the study.
- Active participation or past participation ≤3 months in any other interventional research study.
- Unwilling to participate in all study related activities.
Who the study is looking for
- Ability to provide and provision of signed and dated informed consent form.
- Age 18-80
- Diagnosis of generalized MG.
- On a stable MG prescription medication regimen for the last 3 months.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| HealthPartners Neuroscience Center Coordinator of this site? Confirm its status | Saint Paul | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.