NCT06494254Recruiting
Post-Operative Prediction of PulmonarY Function
Post-Operative Prediction of PulmonarY Function A Pilot Study to Assess the Benefit of Incorporating Regional Ventilation Information in the Prediction of Post-operative Lung Function for Lung Cancer Surgery
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
Prediction of postoperative lung function is currently based on anatomical segment counting (ASC), which incorporates pulmonary function test (PFT) results. Standard PFTs such as spirometry can only measure pulmonary capacity as an average over the entire lung and do not take regional function differences into account. Nuclear medicine is recommended where regional functional imaging is required to inform surgical decisions. However, nuclear medicine scans are expensive, time consuming and not available in all institutions. CT-ventilation imaging is a cheaper and more accessible alternative to nuclear medicine for informing lung cancer patient treatment choices. The primary aim is to quantify the difference between predicted postoperative values of pulmonary function metrics derived from CT ventilation imaging and standard anatomical segment counting method.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 15 (estimated)
- First submitted
- 2 Jul 2024
- Start date
- 25 Jun 2025
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Sydney
- Diseases
- Lung cancer
- NCT number
- NCT06494254
What you commit to
- Study type: Observational
- Planned participants: 15
- From 25 Jun 2025 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Interstitial lung disease.
Other
- Pregnant women.
Who the study is looking for
- Aged 18 years or older.
- ECOG performance status 0-2.
- Lung cancer surgical candidates.
- Undergo SPECT V/Q scans within 8 weeks of registration.
- Undergo BHCT scans within 8 weeks of registration.
- Pulmonary function tests within 8 weeks of registration.
- Willingness to give written informed consent.
- Willingness and ability to comply with the study procedures and visit requirements.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal North Shore Hospital Coordinator of this site? Confirm its status | Saint Leonards | Australia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.