NCT06496425Recruiting
Inspiring Seniors Towards Exercise Promotion to Protect Cognition
Source: ClinicalTrials.gov · Last updated 30 Apr 2026
Brief summary (registry, in English)
The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints. Specific Aims are to determine (1) whether BMS beneficially influences PA behaviors and psychological responses to PA in older adults for 6 months, and (2) whether exercising with BMS differently influences physical and cognitive functioning as well as quality of life in older adults. To test the effects of BMS on PA, participants will be randomly assigned to an exercise intervention that either includes BMS or does not include BMS. Participants will attend a supervised group strength training (ST) (30 minutes per day) and aerobic exercise (AE) (30-50 minutes per day) session for 3 days per week for the first 2 months, 1 day per week for the next 2 months (while encouraging participants to independently perform both AE and ST on other days), and independently for the final 2 months (always with a goal of performing \>150minutes per week AE and 3 days per week of ST for 30 minutes per day).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 12 Jun 2024
- Start date
- 15 May 2024
- Primary completion date
- Oct 2026
- Lead sponsor
- Emory University
- Diseases
- Alzheimer disease
- NCT number
- NCT06496425
What you commit to
- Study type: Interventional
- Planned participants: 80
- From 15 May 2024 to the primary completion date, Oct 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent diagnosis of neurological disorder (e.g., dementia, Parkinson's disease, multiple sclerosis, stroke, etc.).
- Hip/knee/spinal fracture or surgery in the past 6 months.
- Regularly drink \> 14 alcoholic beverages a week or current illicit drug use.
Other illness
- Known exercise contraindications (uncontrolled hypertension, joint problems, diabetes, metabolic conditions etc.).
- Current cancer treatment.
- Stroke or neural impairment in the past 6 months.
- Use of medication for cognitive impairment.
- Meet the threshold for cognitive impairment.
Other
- Unable or unwilling to attend intervention classes.
- Currently participating in any other physical activity or fitness-related research study.
- Meet the threshold for clinical depression.
- Uncorrected hearing or visual impairments.
- Unable to understand the study procedures.
- One of the household members is participating in this study.
Who the study is looking for
- Adults at least 65 years old.
- Ambulatory/capable of walking without pain or the use of assisted walking devices.
- Able to speak and read English.
- Healthy enough to exercise at moderate intensity with or without medical clearance by a primary care physician.
- Living in the community for the duration of the study.
- Having a reliable means of transportation.
- Having a safe place at home or a residential area (at least 6 feet by 6 feet of open space) for unsupervised exercise training.
- Being low-active (\< 60 min/week of moderate-intensity aerobic exercise and no strength training for the last 3 months).
- Having SCC, defined by the Cognitive Change Index (CCI) ≥ 15.
Age in the registry: 65 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Emory University Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
| UNC Greensboro Coordinator of this site? Confirm its status | Greensboro | United States | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.