NCT06497270Active, not recruiting
A 3D Bioprinted Hormone-producing Model for BRCA Mutated Patients After Risk Reducing Surgery: the DISC-OVARY Trial
Source: ClinicalTrials.gov · Last updated 23 Oct 2024
Brief summary (registry, in English)
Selecting theca and granulosa cells from removed ovaries of BRCA1/2mut patients undergoing Risk-reducing salpingo-oophorectomy (RRSO) and developing a 3D bioprinted hormone-producing bioprosthetic model. If efficacy and tolerability are confirmed in vivo, this bioprosthetic model might be used to replace hormones' production in BRCA mutated patients undergoing prophylactic surgery.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 3 (estimated)
- First submitted
- 26 Jun 2024
- Start date
- 10 Oct 2024
- Primary completion date
- 1 Jun 2026
- Lead sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Diseases
- Ovarian cancer
- NCT number
- NCT06497270
What you commit to
- Study type: Interventional
- Planned participants: 3
- From 10 Oct 2024 to the primary completion date, 1 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other malignancies;
- Final histological examination reporting malignant disease (any);
Other
- Desire of fertility sparing.
Who the study is looking for
- Women between 18-40 years old;
- BRCA1/2 germline mutations;
- Completed childbearing;
- Willing to undergo RRSO;
- Negative final histological examination;
- No previous breast cancer.
Age in the registry: 18 years to 40 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Day Hospital Tumori Femminili, Policlinico Universitario Fondazione Agostino Gemelli, IRCCS Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.