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NCT06499129Completed

LevineConservationModelandColorectalPatients

The Effect of Nursing Interventions Based on Levine Conservation Model on Fatigue, Peripheral Neuropathy and Anxiety Levels in Colorectal Cancer Patients Receiving Chemotherapy: A Randomized Controlled Study

Source: ClinicalTrials.gov · Last updated 15 Jan 2026

Brief summary (registry, in English)

Colorectal cancer is one of the most common types of cancer in the world, ranking 3rd among cancers that cause death in men and women. In patients diagnosed with colorectal cancer, chemotherapy treatment is planned to prolong survival as in all other cancer patients. Among the side effects of chemotherapy treatment, it is known that fatigue develops between 50-90%, which is mild for one week in 45% of patients and persists for two weeks in 33%. In the literature, the incidence of chemotherapy-induced peripheral neuropathy is reported to be between 10-100% depending on the type and dose of the drug taken. Alejandro et al. (2013) reported that the incidence of oxaliplatin-related peripheral neuropathy was 84%, which was acute in 74% of patients and permanent in 48%. In addition, anxiety disorders are among the common mental symptoms in cancer patients and their prevalence has been reported to be 10-30%. In this study, it is aimed to reveal the effect of nursing interventions based on Levine's Conservation Model on fatigue, peripheral neuropathy and anxiety levels in colorectal cancer patients receiving chemotherapy treatment.

Status (registry)
Completed
Study type
Interventional
Enrollment
68 (actual)
First submitted
1 Jul 2024
Start date
Jun 2025
Primary completion date
Dec 2025
Lead sponsor
KTO Karatay University
NCT number
NCT06499129

What you commit to

  • Study type: Interventional
  • Participants enrolled: 68
  • From Jun 2025 to the primary completion date, Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Receiving radiotherapy or immunotherapy,

Other illness

  • History of neuropathy or diabetes,
  • History of hypothyroidism, renal failure,
  • Psychiatric diagnosis or ongoing treatment.

Other

  • Hearing, speech and vision problems,

Who the study is looking for

  • Between the ages of 18-75
  • Diagnosed with primary and new colorectal cancer (Stage II and III),
  • The decision to start the FOLFOX treatment protocol has been taken,
  • Having a smartphone,
  • Being literate,
  • Ability to speak and understand Turkish,
  • Open to communication and cooperation.

Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Necmettin Erbakan University
Coordinator of this site? Confirm its status
KonyaTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.