NCT06503666Active, not recruiting
Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults
Source: ClinicalTrials.gov · Last updated 22 Jun 2026
Brief summary (registry, in English)
The proposed hybrid effectiveness-implementation study will systematically adapt the Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (IMARA) curriculum that was previously adapted for South Africa (IMARA-SA) to use in Zambia (will be renamed Zambian Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (ZAIMARA) and evaluate the impact of ZAIMARA on improving adolescent girls and young women HIV testing, HIV and STI incidence, PrEP uptake and sexual risk behaviour. The study will also assess the impact of monthly mental health screening with referral versus a monthly nutrition and exercise screening on peer leaders job retention. We will also examine implementation factors and outcomes associated with ZAIMARA across five sites.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 1200 (estimated)
- First submitted
- 10 Jul 2024
- Start date
- 7 Apr 2025
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Centre for Infectious Disease Research in Zambia
- Diseases
- HIV
- NCT number
- NCT06503666
What you commit to
- Study type: Interventional
- Planned participants: 1200
- From 7 Apr 2025 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- AGYW who are enrolled in other SRH interventions at the time of recruitment (to prevent confounding) or are known to be living with HIV (the needs of AGYW living with HIV are unique and not well-addressed in IMARA-SA, e.g., learning to disclose) will be excluded. Importantly, AGYW who test positive for HIV at the study's baseline assessment will be able to complete the workshops and referred for treatment to avoid stigma.
Other
- AGYW
Who the study is looking for
- Adolescent girls and young women (AGYW)
- 15-19 years-old females (sex assigned at birth)
- Unmarried
- Residing outside the five study catchment areas
- Speak Nyanja, Bemba, or English or a combination (the primary regional languages)
- Willing and able to provide consent (\> 18 years old) and/or assent (\< 18 years old)
- Not known to be living with HIV (i.e., no positive test and not on ART)
- Mother Figures (MF)
- selected to participate by the AGYW
- if not the guardian/mother, agreed upon by the guardian/mother
- \> 24 years-old
- living with or in daily contact with the AGYW
- speak Nyanja, Bemba, or English or a combination
- Willing and able to provide consent
- Peer leaders (ZAIMARA \& Health Promotion)
- live in the community where they will be working
- have prior experience working with young people
- have a minimum grade 12 education
- be proficient in reading and writing English and/or Nyanja or Bemba
- are 22-29 years old for AGYW sessions
- are \>30 years-old for MF sessions
Age in the registry: 15 years to 70 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chainda, Matero, Chelston, Chongwe and Kalingalinga Coordinator of this site? Confirm its status | Lusaka | Zambia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.